Evidence map›Paper›PMID 31331096›Full record

ReviewViruses2019

The Needs for Developing Experiments on Reservoirs in Hantavirus Research: Accomplishments, Challenges and Promises for the Future.

Sarah Madrières, Guillaume Castel, Séverine Murri, Johann Vulin, Philippe Marianneau, Nathalie Charbonnel

Abstract readReview
In one paragraph

Review in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Outbreak of hantavirus disease caused by Puumala virus, Croatia, 2021.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  4. Article
  5. Article
  6. Serological evidence of hantavirus infection in neotropical bats in an urban area of São Paulo State, Brazil.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2023
    Article
  7. Tropism ofViruses · 2023
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarah MadrièresAgence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail, laboratoire de Lyon, Unite Virologie, 69007 Lyon, France.
Guillaume CastelCentre de Biologie pour la Gestion des Populations (CBGP), INRA, CIRAD, IRD, Montpellier SupAgro, Univ Montpellier, 34000 Montpellier, France.
Séverine MurriAgence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail, laboratoire de Lyon, Unite Virologie, 69007 Lyon, France.
Johann VulinAgence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail, laboratoire de Lyon, Unite Virologie, 69007 Lyon, France.
Philippe MarianneauAgence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail, laboratoire de Lyon, Unite Virologie, 69007 Lyon, France.
Nathalie CharbonnelCentre de Biologie pour la Gestion des Populations (CBGP), INRA, CIRAD, IRD, Montpellier SupAgro, Univ Montpellier, 34000 Montpellier, France. nathalie.charbonnel@inra.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to their large geographic distribution and potential high mortality rates in human infections, hantaviruses constitute a worldwide threat to public health. As such, they have been the subject of a large array of clinical, virological and eco-evolutionary studies. Many experiments have been conducted in vitro or on animal models to identify the mechanisms leading to pathogenesis in humans and to develop treatments of hantavirus diseases. Experimental research has also been dedicated to the understanding of the relationship between hantaviruses and their reservoirs. However, these studies remain too scarce considering the diversity of hantavirus/reservoir pairs identified, and the wide range of issues that need to be addressed. In this review, we present a synthesis of the experimental studies that have been conducted on hantaviruses and their reservoirs. We aim at summarizing the knowledge gathered from this research, and to emphasize the gaps that need to be filled. Despite the many difficulties encountered to carry hantavirus experiments, we advocate for the need of such studies in the future, at the interface of evolutionary ecology and virology. They are critical to address emerging areas of research, including hantavirus evolution and the epidemiological consequences of individual variation in infection outcomes.

Indexed as

Biological EvolutionDisease ReservoirsHantavirus InfectionsHost-Pathogen InteractionsHumansModels, BiologicalOrthohantavirusevolutionary ecologyexperimentationshantavirusimmunitypersistencereservoirsspill-oversuper-spreadertransmissionvirology

Identifiers

PMID31331096
PMCPMC6669540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.