Evidence map›Paper›PMID 31331066›Full record

ArticleNutrients2019

Effect of Vasicinone against Paraquat-Induced MAPK/p53-Mediated Apoptosis via the IGF-1R/PI3K/AKT Pathway in a Parkinson's Disease-Associated SH-SY5Y Cell Model.

Da-Tong Ju, Kalaiselvi Sivalingam, Wei-Wen Kuo, Tsung-Jung Ho, Ruey-Lin Chang, Li-Chin Chung, Cecilia Hsuan Day, Vijaya Padma Viswanadha, Po-Hsiang Liao, Chih-Yang Huang

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Article
  6. Review
  7. Effects of Apamin on MPPInternational journal of molecular sciences · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Da-Tong JuDepartment of Neurological Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.
Kalaiselvi SivalingamDepartment of Medical Research, China Medical University Hospital, China Medical University, Taichung 404, Taiwan.
Wei-Wen KuoDepartment of Biological Science and Technology, China Medical University, Taichung 404, Taiwan.ORCID 0000-0002-2097-2240
Tsung-Jung HoDepartment of Chinese Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien 970, Taiwan.
Ruey-Lin ChangSchool of Post-Baccalaureate Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan.
Li-Chin ChungDepartment of Hospital and Health Care Administration, Chia Nan University of Pharmacy & Science, Tainan 717, Taiwan.
Cecilia Hsuan DayDepartment of Nursing, MeiHo University, Pingtung 912, Taiwan.
Vijaya Padma ViswanadhaDepartment of Biotechnology, Bharathiar University, Tamilnadu 641046, India.
Po-Hsiang LiaoCardiovascular and Mitochondria related diseases research center, Hualien Tzu Chi Hospital, Hualien 970, Taiwan.
Chih-Yang HuangDepartment of Medical Research, China Medical University Hospital, China Medical University, Taichung 404, Taiwan. cyhuang@mail.cmu.edu.tw.ORCID 0000-0003-2347-0411
China Medical University · TWTzu Chi University · TWAsia University · TWBharathiar University · INChia Nan University of Pharmacy and Science · TWMeiho University · TWTri-Service General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vasicinone is a quinazoline alkaloid isolated from the

Indexed as

Parkinson DiseaseAlkaloidsApoptosisCell LineCell SurvivalHumansIn Situ Nick-End LabelingMAP Kinase Signaling SystemNeuroprotective AgentsParaquatPhosphatidylinositol 3-KinasesPhosphorylationProto-Oncogene Proteins c-aktReactive Oxygen SpeciesReceptor, IGF Type 1Signal TransductionAlkaloidsIGF1R protein, humanNeuroprotective AgentsParaquatPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReactive Oxygen SpeciesReceptor, IGF Type 1Tumor Suppressor Protein p53vasicinoneapoptosisneuroprotectionparaquatparkinson’s diseasereactive oxygen speciesvasicinone

Identifiers

PMID31331066
PMCPMC6682869
OpenAlexW2963526614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.