Evidence map›Paper›PMID 31330957›Full record

ArticleMolecules (Basel, Switzerland)2019

Chitosan-Based Bioactive Hemostatic Agents with Antibacterial Properties-Synthesis and Characterization.

Julia Radwan-Pragłowska, Marek Piątkowski, Volodymyr Deineka, Łukasz Janus, Viktoriia Korniienko, Evgenia Husak, Viktoria Holubnycha, Iryna Liubchak, Vyacheslav Zhurba, Aleksandra Sierakowska and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 92 citations in OpenAlex.

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  9. Potential benefits of using chitosan and silk fibroin topical hydrogel for managing wound healing and coagulation.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
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  18. Advances in Chitin and Chitosan Science.Molecules (Basel, Switzerland) · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Julia Radwan-PragłowskaFaculty of Chemical Engineering and Technology, Cracow University of Technology, 31-155 Kraków, Poland. jrpraglowska@chemia.pk.edu.pl.
Marek PiątkowskiFaculty of Chemical Engineering and Technology, Cracow University of Technology, 31-155 Kraków, Poland.
Volodymyr DeinekaMedical Institute, Sumy State University, Sumy 40007, Ukraine.
Łukasz JanusFaculty of Chemical Engineering and Technology, Cracow University of Technology, 31-155 Kraków, Poland.
Viktoriia KorniienkoMedical Institute, Sumy State University, Sumy 40007, Ukraine.
Evgenia HusakMedical Institute, Sumy State University, Sumy 40007, Ukraine.
Viktoria HolubnychaMedical Institute, Sumy State University, Sumy 40007, Ukraine.
Iryna LiubchakMedical Institute, Sumy State University, Sumy 40007, Ukraine.
Vyacheslav ZhurbaMedical Institute, Sumy State University, Sumy 40007, Ukraine.
Aleksandra SierakowskaFaculty of Chemical Engineering and Technology, Cracow University of Technology, 31-155 Kraków, Poland.
Maksym PogorielovMedical Institute, Sumy State University, Sumy 40007, Ukraine.ORCID 0000-0001-9372-7791
Dariusz BogdałFaculty of Chemical Engineering and Technology, Cracow University of Technology, 31-155 Kraków, Poland.
Sumy State University · UACracow University of Technology · PL

Funding

H2020-MSCA-RISE 777926 NanoSurfNarodowe Centrum Nauki 2016/23/N/ST8/01273
6 · The paper itself

Abstract

Massive blood loss is responsible for numerous causes of death. Hemorrhage may occur on the battlefield, at home or during surgery. Commercially available biomaterials may be insufficient to deal with excessive bleeding. Therefore novel, highly efficient hemostatic agents must be developed. The aim of the following research was to obtain a new type of biocompatible chitosan-based hemostatic agents with increased hemostatic properties. The biomaterials were obtained in a quick and efficient manner under microwave radiation using l-aspartic and l-glutamic acid as crosslinking agents with no use of acetic acid. Ready products were investigated over their chemical structure by FT-IR method which confirmed a crosslinking process through the formation of amide bonds. Their high porosity above 90% and low density (below 0.08 g/cm

Indexed as

Anti-Bacterial AgentsAntioxidantsBacteriaBiocompatible MaterialsBlood CoagulationChemistry Techniques, SyntheticChitosanHemostaticsMaterials TestingMicrobial Sensitivity TestsMolecular StructurePorositySpectrum AnalysisStructure-Activity RelationshipAnti-Bacterial AgentsAntioxidantsBiocompatible MaterialsChitosanHemostaticsantibacterial biomaterialschitosangreen chemistryhemostatic agentspolymeric materials

Identifiers

PMID31330957
PMCPMC6681126
OpenAlexW2963917558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.