Evidence map›Paper›PMID 31330882›Full record

Trial reportNutrients2019

Faster Gastric Emptying Is Unrelated to Feeding Success in Preterm Infants: Randomized Controlled Trial.

Maria Elisabetta Baldassarre, Antonio Di Mauro, Osvaldo Montagna, Margherita Fanelli, Manuela Capozza, Jennifer L Wampler, Timothy Cooper, Nicola Laforgia

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Shorter Time to Full Preterm Feeding Using Intact Protein Formula: A Randomized Controlled Trial.International journal of environmental research and public health · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Maria Elisabetta BaldassarreNeonatology and Neonatal Intensive Care Unit, Department of Biomedical Science and Human Oncology, University of Bari "Aldo Moro", 70124 Bari, Italy. mariellabaldassarre@gmail.com.ORCID 0000-0003-0590-6664
Antonio Di MauroNeonatology and Neonatal Intensive Care Unit, Department of Biomedical Science and Human Oncology, University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0001-7052-9784
Osvaldo MontagnaNeonatology and Neonatal Intensive Care Unit, Department of Biomedical Science and Human Oncology, University of Bari "Aldo Moro", 70124 Bari, Italy.
Margherita FanelliMedical Statistics, Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0002-0128-9745
Manuela CapozzaNeonatology and Neonatal Intensive Care Unit, Department of Biomedical Science and Human Oncology, University of Bari "Aldo Moro", 70124 Bari, Italy.
Jennifer L WamplerDepartment of Medical Affairs, Mead Johnson Nutrition, Evansville, IN 47721, USA.
Timothy CooperDepartment of Medical Affairs, Mead Johnson Nutrition, Evansville, IN 47721, USA.
Nicola LaforgiaNeonatology and Neonatal Intensive Care Unit, Department of Biomedical Science and Human Oncology, University of Bari "Aldo Moro", 70124 Bari, Italy.
University of Bari Aldo Moro · ITMead Johnson (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the relationship between gastric emptying (GE) time and days to achievement of full enteral feeding (≥140 mL/kg/day) in preterm infants randomly assigned to receive one of two marketed study formulas for the first 14 feeding days: intact protein premature formula (IPF) or extensively hydrolyzed protein (EHF) formula.

methodsIn this triple-blind, controlled, prospective, clinical trial, we report GE time (time to half-emptying, t

resultsMedian GE time at Day 14 was significantly faster for the EHF vs. IPF group overall and in participants who received ≥ 75% study formula intake (

conclusionFeeding IP premature formula vs. EH formula was associated with shorter time to full enteral feeding. However, faster GE time did not predict feeding success and may not be a clinically relevant surrogate for assessing feeding tolerance.

Indexed as

Enteral NutritionFood, FormulatedInfant FormulaFemaleGastric EmptyingHumansInfant, NewbornInfant, PrematureMalePilot Projectsfeeding tolerancegastric emptyinginfantinfant formulaprematureultrasonography

Identifiers

PMID31330882
PMCPMC6683060
OpenAlexW2963593855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.