Evidence map›Paper›PMID 31330857›Full record

ArticleMaterials (Basel, Switzerland)2019

Engineering of Chitosan-Hydroxyapatite-Magnetite Hierarchical Scaffolds for Guided Bone Growth.

Alessandro Pistone, Consuelo Celesti, Elpida Piperopoulos, Deepu Ashok, Arianna Cembran, Antonio Tricoli, David Nisbet

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 45 citations in OpenAlex.

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  5. Recent Advances of Chitosan Formulations in Biomedical Applications.International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Alessandro PistoneDepartment of Engineering, University of Messina, Contrada Di Dio, I-98166 Messina, Italy. pistone@unime.it.
Consuelo CelestiDepartment of Engineering, University of Messina, Contrada Di Dio, I-98166 Messina, Italy.
Elpida PiperopoulosDepartment of Engineering, University of Messina, Contrada Di Dio, I-98166 Messina, Italy.
Deepu AshokLaboratory of Advanced Biomaterials, Research School of Electrical, Energy and Materials Engineering, Australian National University, Canberra ACT 2601, Australia.
Arianna CembranLaboratory of Advanced Biomaterials, Research School of Electrical, Energy and Materials Engineering, Australian National University, Canberra ACT 2601, Australia.
Antonio TricoliNanotechnology Research Laboratory, Research School of Electrical and Energy Engineering, Australian National University, Canberra ACT 2601, Australia.
David NisbetLaboratory of Advanced Biomaterials, Research School of Electrical, Energy and Materials Engineering, Australian National University, Canberra ACT 2601, Australia.
Australian National University · AUUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioabsorbable materials have received increasing attention as innovative systems for the development of osteoconductive biomaterials for bone tissue engineering. In this paper, chitosan-based composites were synthesized adding hydroxyapatite and/or magnetite in a chitosan matrix by in situ precipitation technique. Composites were characterized by optical and electron microscopy, thermogravimetric analyses (TGA), x-ray diffraction (XRD), and in vitro cell culture studies. Hydroxyapatite and magnetite were found to be homogeneously dispersed in the chitosan matrix and the composites showed superior biocompatibility and the ability to support cell attachment and proliferation; in particular, the chitosan/hydroxyapatite/magnetite composite (CS/HA/MGN) demonstrated superior bioactivity with respect to pure chitosan (CS) and to the chitosan/hydroxyapatite (CS/HA) scaffolds.

Indexed as

chitosan/hydroxyapatitemagnetiteosteoconductiontissue engineering

Identifiers

PMID31330857
PMCPMC6678855
OpenAlexW2963018235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.