Evidence map›Paper›PMID 31330813›Full record

ArticleBrain sciences2019

Neural Circuit and Clinical Insights from Intraoperative Recordings During Deep Brain Stimulation Surgery.

Anand Tekriwal, Neema Moin Afshar, Juan Santiago-Moreno, Fiene Marie Kuijper, Drew S Kern, Casey H Halpern, Gidon Felsen, John A Thompson

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Local Field Potentials in Movement Disorders: A Narrative Review.Stereotactic and functional neurosurgery · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Developing Precision Invasive Neuromodulation for Psychiatry.The Journal of neuropsychiatry and clinical neurosciences · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Anand TekriwalDepartment of Neurosurgery, University of Colorado School of Medicine, Aurora, CO 80203, USA.ORCID 0000-0002-6572-1779
Neema Moin AfsharDepartment of Physiology and Biophysics, University of Colorado School of Medicine, Aurora, CO 80203, USA.
Juan Santiago-MorenoMedical Scientist Training Program, University of Colorado School of Medicine, Aurora, CO 80203, USA.
Fiene Marie KuijperDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Drew S KernDepartment of Neurosurgery, University of Colorado School of Medicine, Aurora, CO 80203, USA.
Casey H HalpernDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Gidon FelsenDepartment of Physiology and Biophysics, University of Colorado School of Medicine, Aurora, CO 80203, USA.
John A ThompsonDepartment of Neurosurgery, University of Colorado School of Medicine, Aurora, CO 80203, USA. john.a.thompson@cuanschutz.edu.ORCID 0000-0003-2991-5194
University of Colorado Denver · USStanford University · US

Funding

Neuroscience Training GrantT32NS099042 · NINDS · UNIVERSITY OF COLORADO DENVER · PI Nidia Calero, GIDON S FELSEN · 2016 to 2026
$2.1M
NINDS NIH HHS T32 NS099042
6 · The paper itself

Abstract

Observations using invasive neural recordings from patient populations undergoing neurosurgical interventions have led to critical breakthroughs in our understanding of human neural circuit function and malfunction. The opportunity to interact with patients during neurophysiological mapping allowed for early insights in functional localization to improve surgical outcomes, but has since expanded into exploring fundamental aspects of human cognition including reward processing, language, the storage and retrieval of memory, decision-making, as well as sensory and motor processing. The increasing use of chronic neuromodulation, via deep brain stimulation, for a spectrum of neurological and psychiatric conditions has in tandem led to increased opportunity for linking theories of cognitive processing and neural circuit function. Our purpose here is to motivate the neuroscience and neurosurgical community to capitalize on the opportunities that this next decade will bring. To this end, we will highlight recent studies that have successfully leveraged invasive recordings during deep brain stimulation surgery to advance our understanding of human cognition with an emphasis on reward processing, improving clinical outcomes, and informing advances in neuromodulatory interventions.

Indexed as

deep brain stimulationelectrophysiologyfunctional neurosurgeryhuman cognitionintraoperativelocal field potentialssingle-units

Identifiers

PMID31330813
PMCPMC6681002
OpenAlexW2963677730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.