Evidence map›Paper›PMID 31330768›Full record

ArticleViruses2019

Generation of a Reassortant Influenza A Subtype H3N2 Virus Expressing

Lin Wang, Qinghua Cui, Xiujuan Zhao, Ping Li, Yanyan Wang, Lijun Rong, Ruikun Du

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Lin WangCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Qinghua CuiCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Xiujuan ZhaoCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Ping LiCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Yanyan WangCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Lijun RongDepartment of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA. lijun@uic.edu.
Ruikun DuCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. duzi857@163.com.ORCID 0000-0002-9172-7824
Shandong University of Traditional Chinese Medicine · CNUniversity of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reporter influenza A viruses (IAVs) carrying fluorescent or luminescent genes provide a powerful tool for both basic and translational research. Most reporter IAVs are based on the backbone of either subtype H1N1 viruses, A/Puerto Rico/8/1934 (PR8) or A/WSN/1933, but no reporter subtype H3N2 virus is currently available to our knowledge. Since the IAV subtype H3N2 co-circulates with H1N1 among humans causing annual epidemics, a reporter influenza A subtype H3N2 virus would be highly valuable. In this study, the segments of A/Wyoming/3/03 (NY, H3N2) virus encoding hemagglutinin and neuraminidase, respectively, were reassorted with the six internal genes of PR8 where the NS gene was fused with a

Indexed as

Gene Expression Regulation, ViralGenes, ReporterAnimalsAntiviral AgentsCell LineDogsGene ExpressionHumansInfluenza A Virus, H3N2 SubtypeInfluenza, HumanLuciferasesMadin Darby Canine Kidney CellsReassortant VirusesViral Nonstructural ProteinsAntiviral AgentsINS1 protein, influenza virusLuciferasesViral Nonstructural Proteinsinfluenza A virusreassortantreporter virussubtype H3N2

Identifiers

PMID31330768
PMCPMC6669691
OpenAlexW2964231857

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.