Evidence map›Paper›PMID 31330597›Full record

ArticlePhysical review. E2019

Chaotic tip trajectories of a single spiral wave in the presence of heterogeneities.

Daniel M Lombardo, Wouter-Jan Rappel

Abstract read
In one paragraph

Article in Physical review. E, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Daniel M LombardoDepartment of Physics, University of California San Diego, San Diego, California 92093, USA.
Wouter-Jan RappelDepartment of Physics, University of California San Diego, San Diego, California 92093, USA.

Funding

Patient-Directed Computational Analysis of Atrial FibrillationR01HL122384 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WOUTER-JAN RAPPEL · 2015 to 2026
$5.3M
Determining strength and temporal stability of rotational and focal sources during human atrial fibrillationR21HL145500 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RAPPEL, WOUTER-JAN · 2019 to 2020
$236k
NHLBI NIH HHS R01 HL122384NHLBI NIH HHS R21 HL145500
6 · The paper itself

Abstract

Spiral waves have been observed in a variety of physical, chemical, and biological systems. They play a major role in cardiac arrhythmias, including fibrillation, where the observed irregular activation patterns are generally thought to arise from the continuous breakup of multiple unstable spiral waves. Using spatially extended simulations of different electrophysiological models of cardiac tissue, we show that a single spiral wave in the presence of heterogeneities can display chaotic tip trajectories, consistent with fibrillation. We also show that the simulated spiral tip dynamics, including chaotic trajectories, can be captured by a simple particle model which only describes the dynamics of the spiral tip. This shows that spiral wave breakup, or interactions with other waves, are not necessary to initiate chaos in spiral waves.

Identifiers

PMID31330597
PMCPMC7296979

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.