Evidence map›Paper›PMID 31330093›Full record

ReviewPediatric blood & cancer2019

Management of chronic myeloid leukemia in children and adolescents: Recommendations from the Children's Oncology Group CML Working Group.

Uma Athale, Nobuko Hijiya, Briana C Patterson, John Bergsagel, Jeffrey R Andolina, Henrique Bittencourt, Kirk R Schultz, Michael J Burke, Michele S Redell, E Anders Kolb and 1 more

Open access · greenAbstract readReview
In one paragraph

Review in Pediatric blood & cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Dynamics ofHemaSphere · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. EarlyCancers · 2025
    Article
  9. Article
  10. [How I treat pediatric chronic myeloid leukemia].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
    Review
  11. Article
  12. Aiming Targeted Drug Development at Rare Pediatric Malignancies.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. The Outcome of Pediatric Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Experience from a Referral Center in South India.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 2 countries.

Uma AthaleDivision of Hematology/Oncology, McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario, Canada.ORCID 0000-0003-3236-6560
Nobuko HijiyaDivision of Hematology/Oncology, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0002-0199-054X
Briana C PattersonDivision of Pediatric Endocrinology and Metabolism, Emory University School of Medicine, Atlanta, Georgia.
John BergsagelDivision of Hematology/Oncology, Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia.
Jeffrey R AndolinaDivision of Hematology/Oncology, Golisano Children's Hospital, University of Rochester, Rochester, New York.ORCID 0000-0001-6502-6859
Henrique BittencourtDivision of Hematology/Oncology, Ste Justine University Hospital Center, Montreal, Quebec, Canada.
Kirk R SchultzDivision of Hematology/Oncology/BMT, British Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.
Michael J BurkeDivision of Hematology/Oncology, Children's Hospital of Wisconsin, Milwaukee, Wisconsin.
Michele S RedellDivision of Hematology/Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
E Anders KolbNemours Center for Cancer and Blood Disorders, Nemours/Alfred I DuPont Hospital for Children, Wilmington, Delaware.
Donna L JohnstonDivision of Hematology/Oncology, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.ORCID 0000-0001-6145-9809
Emory University · USBaylor College of Medicine · USBC Children's Hospital · CACentre Hospitalier Universitaire Sainte-Justine · CAChildren's Hospital of Eastern Ontario · CAChildren's Hospital of Wisconsin · USDuPont (United States) · USGolisano Children's Hospital · USMcMaster Children's Hospital · CANorthwestern University · US

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
NCI NIH HHS U10 CA180886NIH HHS U10CA180886
6 · The paper itself

Abstract

Chronic myeloid leukemia (CML) accounts for 2-3% of leukemias in children under 15 and 9% in adolescents aged 15-19. The diagnosis and management of CML in children, adolescents, and young adults have several differences compared to that in adults. This review outlines the diagnosis and management of the underlying disease as well as challenges that can occur when dealing with CML in this patient population.

Indexed as

AdolescentChildChild, PreschoolFemaleHumansLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMalePractice Guidelines as TopicCMLpediatricrecommendations

Identifiers

PMID31330093
PMCPMC6944522
OpenAlexW2950424869

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.