ArticlePloS one2019
Chloroplast-localized iron superoxide dismutases FSD2 and FSD3 are functionally distinct in Arabidopsis.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Multifaceted roles of superoxide dismutases (SODs) in cellular homeostasis and cancer progression: Redox regulation and therapeutic implications.Journal of medical biochemistry · 2026Article
- The cryo-EM structure of Photosystem I from Chromera velia with a bound superoxide dismutase heterodimer.Nature communications · 2025Article
- Overexpression of milk thistle SOD gene enhances drought tolerance in tobacco by improving photosynthesis and photoprotection.Scientific reports · 2025Article
- Cesium Accumulation Patterns and Stress Response in Hydroponic Radish (Plants (Basel, Switzerland) · 2025Article
- Phosphorus Supplementation Enhances Growth and Antioxidant Defense Against Cadmium Stress in Cotton.Antioxidants (Basel, Switzerland) · 2025Article
- How the Ectopic Expression of the BarleyInternational journal of molecular sciences · 2025Article
- Architecture of the spinach plastid-encoded RNA polymerase.Nature communications · 2024Article
- Integrative analysis of transcriptome and metabolome provides insights into the mechanisms of leaf variegation in Heliopsis helianthoides.BMC plant biology · 2024Article
- Role of mitochondria and chloroplasts during stomatal closure: Subcellular location of superoxide and HJournal of biosciences · 2024Article
- Physiological Characteristics and Transcriptome Analysis of Exogenous Brassinosteroid-Treated Kiwifruit.International journal of molecular sciences · 2023Article
- Article
- Molecular and Biochemical Analysis of Duplicated Cytosolic CuZn Superoxide Dismutases of Rice andFrontiers in plant science · 2022Article
- Differences in Cadmium Accumulation, Detoxification and Antioxidant Defenses between Contrasting Maize Cultivars Implicate a Role of Superoxide Dismutase in Cd Tolerance.Antioxidants (Basel, Switzerland) · 2021Article
- Article
- Signaling Toward Reactive Oxygen Species-Scavenging Enzymes in Plants.Frontiers in plant science · 2020Review
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2 authors.
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Abstract
Superoxide dismutases (SODs) protect against reactive oxygen species (ROS) by detoxifying superoxide. Three types of SOD are present in plants: FeSOD, CuSOD, and MnSOD. The Arabidopsis thaliana genome contains three FeSOD genes, in which two (FSD2, and FSD3) are targeted to chloroplast thylakoids. Loss of FSD2 or FSD3 expression impairs growth and causes leaf bleaching. FSD2 and FSD3 form heterocomplexes present in chloroplast nucleoids, raising the question of whether FSD2 and FSD3 are functionally interchangeable. In this study, we examined how loss of FSD2 or FSD3 expression affects photosynthetic processes and whether overexpression of one compensates for loss of the other. Whereas loss of the cytosolic FSD1 had little effect, an fsd2 mutant exhibited increased superoxide production, reduced chlorophyll levels, lower PSII efficiency, a lower rate of CO2 assimilation, but elevated non-photochemical quenching (NPQ). In contrast, fsd3 mutants failed to survive beyond the seedling stage and overexpression of FSD2 could not rescue the seedlings. Overexpression of FSD3 in an fsd2 mutant, however, partially reversed the fsd2 mutant phenotype resulting in improved growth characteristics. Overexpression of FSD2 or FSD3, either individually or together, had little effect. These results indicate that, despite functioning as FeSODs, FSD2 and FSD3 are functionally distinct.
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