Evidence map›Paper›PMID 31329553›Full record

ArticleIEEE transactions on ultrasonics, ferroelectrics, and frequency control2019

Hierarchical Motion Estimation With Bayesian Regularization in Cardiac Elastography: Simulation and In Vivo Validation.

Rashid Al Mukaddim, Nirvedh H Meshram, Carol C Mitchell, Tomy Varghese

Abstract readValidation Study
In one paragraph

Article in IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Lagrangian deformation tracking for strain imaging.Progress in biomedical engineering (Bristol, England) · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Bayesian Regularized Strain Imaging for Assessment of Murine Cardiac Function In vivo.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2021
    Article
  8. Subaperture Processing-Based Adaptive Beamforming for Photoacoustic Imaging.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021
    Article
  9. Spatiotemporal Bayesian Regularization for Cardiac Strain Imaging: Simulation andIEEE open journal of ultrasonics, ferroelectrics, and frequency control · 2021
    Article
  10. Improving Ultrasound Lateral Strain Estimation Accuracy using Log Compression of Regularized Correlation Function.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2020
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rashid Al Mukaddim
Nirvedh H Meshram
Carol C Mitchell
Tomy Varghese

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
Real-time Ultrasonic Monitoring of Tumor AblationR01CA112192 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI VARGHESE, TOMY · 2007 to 2017
$2.6M
Ultrasonic and Photoacoustic Imaging System for Cancer & Cardiovascular ResearchS10OD018505 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI VARGHESE, TOMY · 2015 to 2015
$908k
NCI NIH HHS P30 CA014520NCI NIH HHS R01 CA112192NIH HHS S10 OD018505
6 · The paper itself

Abstract

Cardiac elastography (CE) is an ultrasound-based technique utilizing radio-frequency (RF) signals for assessing global and regional myocardial function. In this work, a complete strain estimation pipeline for incorporating a Bayesian regularization-based hierarchical block-matching algorithm, with Lagrangian motion description and myocardial polar strain estimation is presented. The proposed regularization approach is validated using finite-element analysis (FEA) simulations of a canine cardiac deformation model that is incorporated into an ultrasound simulation program. Interframe displacements are initially estimated using a hierarchical motion estimation framework. Incremental displacements are then accumulated under a Lagrangian description of cardiac motion from end-diastole (ED) to end-systole (ES). In-plane Lagrangian finite strain tensors are then derived from the accumulated displacements. Cartesian to cardiac coordinate transformation is utilized to calculate radial and longitudinal strains for ease of interpretation. Benefits of regularization are demonstrated by comparing the same hierarchical block-matching algorithm with and without regularization. Application of Bayesian regularization in the canine FEA model provided improved ES radial and longitudinal strain estimation with statistically significant ( ) error reduction of 48.88% and 50.16%, respectively. Bayesian regularization also improved the quality of temporal radial and longitudinal strain curves with error reductions of 78.38% and 86.67% ( ), respectively. Qualitative and quantitative improvements were also visualized for in vivo results on a healthy murine model after Bayesian regularization. Radial strain elastographic signal-to-noise ratio (SNR

Indexed as

AlgorithmsAnimalsBayes TheoremComputer SimulationDogsElasticity Imaging TechniquesFinite Element AnalysisHeartModels, AnimalMotionSignal-To-Noise Ratio

Identifiers

PMID31329553
PMCPMC6855404

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.