ArticleEuropean journal of rheumatology2019
Treat-to-target concept implementation for evaluating rheumatoid arthritis patients in daily practice.
Article in European journal of rheumatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Effectiveness of a treat-to-target strategy in patients with moderate to severely active rheumatoid arthritis treated with abatacept.Arthritis research & therapy · 2023Trial
- Management of Rheumatoid Arthritis With a Digital Health Application: A Multicenter, Pragmatic Randomized Clinical Trial.JAMA network open · 2023Trial
- Visit adherence and clinical, inflammatory, and patient-reported outcomes in rheumatoid arthritis: a cross-sectional study.Clinical rheumatology · 2026Article
- Patient self-assessment and virtual visit-based treatment decisions in rheumatoid arthritis: results from the multicentre Telemedicine in Rheumatoid Arthritis trial.EULAR rheumatology open · 2025Article
- Real-world usage of digital health applications (DiGA) in rheumatology: results from a German patient survey.Rheumatology international · 2023Observational
- Establishment and verification of a nomogram and a preliminary study on predicting the clinical response of conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) in rheumatoid arthritis patients.Annals of translational medicine · 2022Article
- Implementation of the treat-to-target approach and treatment satisfaction in patients with rheumatoid arthritis: perspectives of Chinese rheumatologists.Clinical rheumatology · 2022Article
- Belgian rheumatologists' preferences regarding measures of disease activity in patients with rheumatoid arthritis: results from a mixed-methods study.Rheumatology international · 2022Article
- Implementation of the Treat-to-Target Concept in Evaluation of Psoriatic Arthritis Patients.Journal of clinical medicine · 2021Article
- TELERA-Asynchronous TELEmedicine for Patients With Rheumatoid Arthritis: Study Protocol for a Prospective, Multi-Center, Randomized Controlled Trial.Frontiers in medicine · 2021Article
- Acceptance, Usage, and Barriers of Electronic Patient-Reported Outcomes Among German Rheumatologists: Survey Study.JMIR mHealth and uHealth · 2020Article
- Disease activity-based management of rheumatoid arthritis in Dutch daily clinical practice has improved over the past decade.Clinical rheumatology · 2020Observational
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe aimed to assess the implementation of the treat-to-target (T2T) concept in rheumatoid arthritis (RA) patients in daily practice.
methodsAll RA patients visiting one of the 7 academic medical centers in Israel in June 2015 with at least 3 previous clinic visits were included in this study. A common questionnaire was used to collect data from patients' medical records, and two independent rheumatologists evaluated the collected data for the implementation of the T2T concept. The associations between T2T implementation and the categorical and continuous variables were assessed.
resultsThe study included 724 patients with a mean (standard deviation) age of 62.6 (13.97) years and 575 (80.4%) of them were women. Four centers used more than one scoring method, with Disease Activity Score-28 and Clinical Disease Activity Index) being most commonly used. Only 276 (38.1%) patients had disease score results in ≥3 visits, and the T2T recommendations were implemented for 245 (33.8%) of the 724 patients. The rate of implementation was higher in younger (p=0.028) rheumatoid factor-positive patients (p=0.011) and varied between centers (11.1%-87% p<0.0001). T2T implementation did not correlate to gender, place of residence, education, tobacco use, treatment regimens, and presence of erosions or comorbidities.
conclusionThe T2T concept was implemented on only 33.8% of patients and was not affected by RA disease severity. Further studies are needed to determine the reasons for this deviation from the T2T standard of care for RA as well as its consequences.
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