Evidence map›Paper›PMID 31329342›Full record

ArticleNMR in biomedicine2019

SNR optimized

Arjan D Hendriks, Wybe J M van der Kemp, Peter R Luijten, Natalia Petridou, Dennis W J Klomp

Abstract read
In one paragraph

Article in NMR in biomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Creatine kinase imaging (CKI) for in vivo whole-brain mapping of creatine kinase reaction kinetics.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. An Integrated BNMR in biomedicine · 2025
    Article
  3. FunctionalNMR in biomedicine · 2025
    Article
  4. Interleaved Whole BrainNMR in biomedicine · 2025
    Article
  5. Article
  6. 17β-Estradiol Effects in Skeletal Muscle: ADiagnostics (Basel, Switzerland) · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. SNR optimizedNMR in biomedicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Arjan D HendriksDepartment of Radiology, University Medical Center Utrecht, Utrecht, the Netherlands.ORCID 0000-0002-0363-2471
Wybe J M van der KempDepartment of Radiology, University Medical Center Utrecht, Utrecht, the Netherlands.ORCID 0000-0003-1123-2352
Peter R LuijtenDepartment of Radiology, University Medical Center Utrecht, Utrecht, the Netherlands.
Natalia PetridouDepartment of Radiology, University Medical Center Utrecht, Utrecht, the Netherlands.
Dennis W J KlompDepartment of Radiology, University Medical Center Utrecht, Utrecht, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Energy metabolism of the human visual cortex was investigated by performing

introductionThe human brain is known to be the main glucose demanding organ of the human body and neuronal activity can increase this energy demand. In this study we investigate whether alterations in pH during activation of the brain can be observed with MRS, focusing on the mitochondrial inorganic phosphate (Pi) pool as potential marker of energy demand.

methodsSix participants were scanned with 16 consecutive

resultsThe targeted resonance downfield of the main Pi peak could be distinguished, indicating the high SNR of the

conclusionOverall, the downfield peak of Pi could be observed, revealing opportunities and considerations to measure specific acidity (pH) effects in the human visual cortex.

Indexed as

Magnetic Resonance SpectroscopyPhotic StimulationSignal-To-Noise RatioAdultExtracellular SpaceFemaleHumansHydrogen-Ion ConcentrationMaleMitochondriaPhosphocreatinePhosphorusVisual CortexYoung AdultPhosphocreatinePhosphorus31P MRSfMRSmitochondrial PipHphosphorus spectroscopyvisual cortex

Identifiers

PMID31329342
PMCPMC6900119

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.