Evidence map›Paper›PMID 31329250›Full record

ReviewAdvances in nutrition (Bethesda, Md.)2020

Recent Research on the Health Benefits of Blueberries and Their Anthocyanins.

Wilhelmina Kalt, Aedin Cassidy, Luke R Howard, Robert Krikorian, April J Stull, Francois Tremblay, Raul Zamora-Ros

Open access · hybridAbstract readReview
In one paragraph

Review in Advances in nutrition (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 237 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
237citing papers in PubMed, 6 pooled it
18.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

237 citing papers in PubMed, 6 syntheses or guidelines pooled it, 621 citations in OpenAlex.

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177 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 4 countries.

Wilhelmina KaltAgriculture and Agri-Food Canada, Kentville Research and Development Centre, Kentville, Nova Scotia, Canada (retired).
Aedin CassidyDepartment of Nutrition, Norwich Medical School, University of East Anglia, Norwich, United Kingdom.
Luke R HowardDepartment of Food Science, University of Arkansas, Fayetteville, AR, USA.
Robert KrikorianDepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati Academic Health Center, Cincinnati, OH, USA.
April J StullDepartment of Human Ecology, University of Maryland Eastern Shore, Princess Anne, MD, USA.
Francois TremblayDepartment of Ophthalmology and Visual Sciences and Department of Physiology and Biophysics, Dalhousie University, Halifax, Nova Scotia, Canada.
Raul Zamora-RosUnit of Nutrition and Cancer, Cancer Epidemiology Research Programme, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.
Agriculture and Agri-Food Canada · CADalhousie University · CAInstitut d'Investigació Biomédica de Bellvitge · ESUniversity of Arkansas at Fayetteville · USUniversity of Cincinnati Medical Center · USUniversity of East Anglia · GBUniversity of Maryland Eastern Shore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Awareness of the human health benefits of blueberries is underpinned by a growing body of positive scientific evidence from human observational and clinical research, plus mechanistic research using animal and in vitro models. Blueberries contain a large number of phytochemicals, including abundant anthocyanin pigments. Of their various phytochemicals, anthocyanins probably make the greatest impact on blueberry health functionality. Epidemiological studies associate regular, moderate intake of blueberries and/or anthocyanins with reduced risk of cardiovascular disease, death, and type 2 diabetes, and with improved weight maintenance and neuroprotection. These findings are supported by biomarker-based evidence from human clinical studies. Among the more important healthful aspects of blueberries are their anti-inflammatory and antioxidant actions and their beneficial effects on vascular and glucoregulatory function. Blueberry phytochemicals may affect gastrointestinal microflora and contribute to host health. These aspects have implications in degenerative diseases and conditions as well as the aging process. More evidence, and particularly human clinical evidence, is needed to better understand the potential for anthocyanin-rich blueberries to benefit public health. However, it is widely agreed that the regular consumption of tasty, ripe blueberries can be unconditionally recommended.

Indexed as

Blueberry PlantsDietAnimalsAnthocyaninsAnti-Inflammatory AgentsAntioxidantsBiomedical ResearchBody WeightCardiovascular DiseasesDiabetes Mellitus, Type 2Diet, HealthyFruitGastrointestinal MicrobiomeHealth StatusHumansNeuroprotective AgentsAnthocyaninsAnti-Inflammatory AgentsAntioxidantsNeuroprotective Agentsanthocyaninberriescardiovascularcognitiondiabetesobesityprocessingvision

Identifiers

PMID31329250
PMCPMC7442370
OpenAlexW2963957709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.