ArticleJournal of dental research2019
Activation of the STAT1 Pathway Accelerates Periodontitis in
Article in Journal of dental research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 40 citations in OpenAlex.
- Exploring the Therapeutic Potential of Epigallocatechin-3-gallate (Green Tea) in Periodontitis Using Network Pharmacology and Molecular Modeling Approach.International journal of molecular sciences · 2025Article
- Exploring the toxicological effects of DOTP exposure on periodontitis by combining molecular docking and molecular dynamics simulations.Scientific reports · 2025Article
- Multi-omics investigation ofmSystems · 2025Article
- Fumarate Restrains Alveolar Bone Restoration via Regulating H3K9 Methylation.Journal of dental research · 2024Article
- Dynamic changes in macrophage polarization during the resolution phase of periodontal disease.Immunity, inflammation and disease · 2024Article
- Article
- Macrophage neogenin deficiency exacerbates myocardial remodeling and inflammation after acute myocardial infarction through JAK1-STAT1 signaling.Cellular and molecular life sciences : CMLS · 2023Article
- Four-Octyl itaconate ameliorates periodontal destruction via Nrf2-dependent antioxidant system.International journal of oral science · 2022Article
- Global proteomics of fibroblast cells treated with bacterial cyclic dinucleotides, c-di-GMP and c-di-AMP.Journal of oral microbiology · 2022Article
- Glycogen synthase kinase-3β (GSK-3β) deficiency inactivates the NLRP3 inflammasome-mediated cell pyroptosis in LPS-treated periodontal ligament cells (PDLCs).In vitro cellular & developmental biology. Animal · 2021Article
- Periodontitis aggravates kidney injury by upregulating STAT1 expression in a mouse model of hypertension.FEBS open bio · 2021Article
- Shared Molecular Mechanisms between Alzheimer's Disease and Periodontitis Revealed by Transcriptomic Analysis.BioMed research international · 2021Article
- Polarized Macrophages in Periodontitis: Characteristics, Function, and Molecular Signaling.Frontiers in immunology · 2021Review
- Parathyroid hormone increases alveolar bone homoeostasis during orthodontic tooth movement in rats with periodontitis via crosstalk between STAT3 and β-catenin.International journal of oral science · 2020Article
- Inhibition of Cathepsin K Alleviates Autophagy-Related Inflammation in Periodontitis-Aggravating Arthritis.Infection and immunity · 2020Article
- Low-intensity pulsed ultrasound upregulates osteogenesis under inflammatory conditions in periodontal ligament stem cells through unfolded protein response.Stem cell research & therapy · 2020Article
- Mechanical load-induced HStem cell research & therapy · 2020Article
- Predictive modeling of stem cell suppression by inflammatory cytokine networks: A synthetic transcriptomic approach for periodontal tissue engineering.Journal of oral biology and craniofacial researchArticle
- Pre-clinical and clinical efficacy of curcumin as an anti-inflammatory agent for periodontitis. A systematic review.Revista cientifica odontologica (Universidad Cientifica del Sur)Review
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early studies on the etiology and pathogenesis of hypertension have shown that it has a considerable association with inflammation and the immune response as well as periodontitis. Clinical studies have also shown that hypertension can promote the periodontal tissue destruction caused by periodontitis. However, the underlying mechanisms remain unclear. This study aimed to explore the possible mechanisms of how hypertension aggravates periodontitis. Treatment with or without the signal transducer and activator of transcription 1 (STAT1) inhibitor fludarabine was performed in an endothelial nitric oxide synthase gene knockout-related (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.