Evidence map›Paper›PMID 31329044›Full record

ArticleJournal of dental research2019

The Subgingival Microbiome Relationship to Periodontal Disease in Older Women.

R J Genco, M J LaMonte, D I McSkimming, M J Buck, L Li, K M Hovey, C A Andrews, Y Sun, M Tsompana, W Zheng and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of dental research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Hormonal Environment Shapes the Oral Microbiome.Advances in experimental medicine and biology · 2025
    Review
  9. Article
  10. The oral-gut microbiome axis in health and disease.Nature reviews. Microbiology · 2024
    Review
  11. Association Between Oral Microbiota and Gastrointestinal/Extra-Gastrointestinal Diseases.The Korean journal of helicobacter and upper gastrointestinal research · 2024
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

R J Genco1 Departments of Oral Biology, and Microbiology and Immunology, and Center for Microbiome Research, University at Buffalo, Buffalo, NY, USA.
M J LaMonte2 Department of Epidemiology and Environmental Health, University at Buffalo, Buffalo, NY, USA.
D I McSkimming3 Genome, Environment, and Microbiome Community of Excellence, University at Buffalo, Buffalo, NY, USA.
M J Buck4 Department of Biochemistry, New York State Center of Excellence in Bioinformatics and Life Sciences, University at Buffalo, Buffalo, NY, USA.
L Li5 Department of Computer Science and Engineering, University at Buffalo, Buffalo, NY, USA.
K M Hovey2 Department of Epidemiology and Environmental Health, University at Buffalo, Buffalo, NY, USA.
C A Andrews6 Department of Ophthalmology, University of Michigan, Ann Arbor, MI, USA.
Y Sun7 Departments of Immunology, Computer Science and Engineering, and Bioinformatics, University at Buffalo, Buffalo, NY, USA.
M Tsompana4 Department of Biochemistry, New York State Center of Excellence in Bioinformatics and Life Sciences, University at Buffalo, Buffalo, NY, USA.
W Zheng5 Department of Computer Science and Engineering, University at Buffalo, Buffalo, NY, USA.
H R Banack2 Department of Epidemiology and Environmental Health, University at Buffalo, Buffalo, NY, USA.
V Murugaiyan3 Genome, Environment, and Microbiome Community of Excellence, University at Buffalo, Buffalo, NY, USA.
J Wactawski-Wende2 Department of Epidemiology and Environmental Health, University at Buffalo, Buffalo, NY, USA.
University at Buffalo, State University of New York · USUniversity of Michigan–Ann Arbor · US

Funding

Oral Microbiome and Periodontitis: A Prospective Study in Postmenopausal WomenR01DE024523 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WACTAWSKI-WENDE, JEAN · 2014 to 2018
$3.8M
BONE MINERAL DENSITY AS A PREDICTOR OF PERIODONTITISR01DE013505 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WACTAWSKI-WENDE, JEAN · 2002 to 2005
$1.9M
Developing Advanced Algorithms to Address Major Computational Challenges in Current Microbiome ResearchR01AI125982 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI SUN, YIJUN · 2016 to 2018
$973k
VANGUARD CENTER FOR WOMEN'S HEALTH INITIATIVEN01WH032122 · WH · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI TREVISAN, MAURIZIO · 1993 to 2000
$927k
METABOLIC SYNDROME AND PERIODONTITIS IN POSTMENOPAUSAL WOMENR03DE022654 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI LAMONTE, MICHAEL J · 2012 to 2013
$311k
NIAID NIH HHS R01 AI125982NIDCR NIH HHS R01 DE013505NIDCR NIH HHS R01 DE024523NIDCR NIH HHS R03 DE022654WHI NIH HHS N01 WH032122
6 · The paper itself

Abstract

Understanding of the oral microbiome in relation to periodontal disease in older adults is limited. The composition and diversity of the subgingival microflora and their oligotypes in health and levels of periodontal disease were investigated in this study on older postmenopausal women. The 16S rRNA gene was sequenced using the Illumina MiSeq platform in 1,206 women aged 53 to 81 y. Presence and severity of periodontal disease were defined by Centers for Disease Control and Prevention/American Academy of Periodontology criteria. Composition of the microbiome was determined by 16S rRNA amplicon sequencing and the abundance of taxa described by the centered log

Indexed as

MicrobiotaAgedAged, 80 and overBacteriaFemaleGingivaHumansMiddle AgedPeriodontitisRNA, Ribosomal, 16SRNA, Ribosomal, 16Sbacteriamenopausemicrobiologynext-generation sequencingoligotypesoral health

Identifiers

PMID31329044
PMCPMC6651762
OpenAlexW2963063283

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.