Evidence map›Paper›PMID 31328891›Full record

ArticleJournal of the International AIDS Society2019

A longitudinal study of associations between HIV-related stigma, recent violence and depression among women living with HIV in a Canadian cohort study.

Carmen H Logie, Natania Marcus, Ying Wang, Angela Kaida, Patricia O'Campo, Uzma Ahmed, Nadia O'Brien, Valerie Nicholson, Tracey Conway, Alexandra de Pokomandy and 3 more

Abstract read
In one paragraph

Article in Journal of the International AIDS Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  20. Syndemics and clinical science.Nature medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Carmen H LogieFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-8035-433X
Natania MarcusDepartment of Applied Psychology and Human Development, University of Toronto, Toronto, Ontario, Canada.
Ying WangFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.
Angela KaidaFaculty of Health Sciences, Simon Fraser University, Vancouver, British Columbia, Canada.
Patricia O'CampoSt. Michael's Hospital, Toronto, Ontario, Canada.
Uzma AhmedFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.
Nadia O'BrienDepartment of Family Medicine, McGill University, Montreal, Quebec, Canada.ORCID 0000-0003-2877-6268
Valerie NicholsonFaculty of Health Sciences, Simon Fraser University, Vancouver, British Columbia, Canada.
Tracey ConwayWomen's College Research Institute, Women's College Hospital, Toronto, Ontario, Canada.
Alexandra de PokomandyDepartment of Family Medicine, McGill University, Montreal, Quebec, Canada.
Mylène FernetDepartment of Sexology, Université du Québec à Montréal, Montreal, Quebec, Canada.
Mona LoutfyWomen's College Research Institute, Women's College Hospital, Toronto, Ontario, Canada.
CHIWOS Research Team

Funding

CIHR CTN 262
6 · The paper itself

Abstract

introductionWomen living with HIV (WLHIV) experience stigma and elevated exposure to violence in comparison with HIV-negative women. We examined the mediating role of experiencing recent violence in the relationship between stigma and depression among WLHIV in Canada.

methodsWe conducted a cohort study with WLHIV in three Canadian provinces. Recent violence was assessed through self-reported experiences of control, physical, sexual or verbal abuse in the past three months. At Time 1 (2013-2015) three forms of stigma were assessed (HIV-related, racial, gender) and at Time 2 (2015-2017) only HIV-related stigma was assessed. We conducted structural equation modelling (SEM) using the maximum likelihood estimation method with Time 1 data to identify direct and indirect effects of gender discrimination, racial discrimination and HIV-related stigma on depression via recent violence. We then conducted mixed effects regression and SEM using Time 1 and Time 2 data to examine associations between HIV-related stigma, recent violence and depression.

resultsAt Time 1 (n = 1296), the direct path from HIV-related stigma (direct effect: β = 0.200, p < 0.001; indirect effect: β = 0.014, p < 0.05) to depression was significant; recent violence accounted for 6.5% of the total effect. Gender discrimination had a significant direct and indirect effect on depression (direct effect: β = 0.167, p < 0.001; indirect effect: β = 0.050, p < 0.001); recent violence explained 23.15% of the total effect. Including Time 1 and Time 2 data (n = 1161), mixed-effects regression results indicate a positive relationship over time between HIV-related stigma and depression (Acoef: 0.04, 95% CI: 0.03, 0.06, p < 0.001), and recent violence and depression (Acoef: 1.95, 95% CI: 0.29, 4.42, p < 0.05), controlling for socio-demographics. There was a significant interaction between HIV-related stigma and recent violence with depression (Acoef: 0.04, 95% CI: 0.01, 0.07, p < 0.05). SEM analyses reveal that HIV-related stigma had a significant direct and indirect effect on depression over time (direct effect: β = 0.178, p < 0.001; indirect effect: β = 0.040, p < 0.001); recent violence experiences accounted for 51% of the total effect.

conclusionsOur findings suggest that HIV-related stigma is associated with increased experiences of recent violence, and both stigma and violence are associated with increased depression among WLHIV in Canada. There is an urgent need for trauma-informed stigma interventions to address stigma, discrimination and violence.

Indexed as

Social StigmaViolenceAdultCanadaCohort StudiesDepressionFemaleHIV-1HIV InfectionsHumansLongitudinal StudiesMiddle AgedRacismSelf ReportdepressiongenderHIVstigmaviolencewomen

Identifiers

PMID31328891
PMCPMC6643300

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.