Evidence map›Paper›PMID 31328888›Full record

ArticleClinical and translational science2019

Clinical Pharmacology-Driven Translational Research to Optimize Bedside Therapeutics of Sotalol Therapy.

Elyes Dahmane, Kathy Tang, Jogarao V S Gobburu, T Joseph Mattingly, Brent N Reed, Vincent Y See, Joshuha Ayres, Vijay Ivaturi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Multicenter Analysis of Dosing Protocols for Sotalol Initiation.Journal of cardiovascular pharmacology and therapeutics · 2020
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Elyes DahmaneDepartment of Pharmacy Practice and Science, Center for Translational Medicine, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
Kathy TangEmory University Hospital Midtown, Atlanta, Georgia, USA.
Jogarao V S GobburuDepartment of Pharmacy Practice and Science, Center for Translational Medicine, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
T Joseph MattinglyDepartment of Pharmacy Practice and Science, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
Brent N ReedDepartment of Pharmacy Practice and Science, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
Vincent Y SeeCardiovascular Medicine Division, Department of Medicine, School of Medicine, University of Maryland, Baltimore, Maryland, USA.
Joshuha AyresUniversity of Maryland Medical Center, Baltimore, Maryland, USA.
Vijay IvaturiDepartment of Pharmacy Practice and Science, Center for Translational Medicine, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
University of Maryland, Baltimore · USEmory University Hospital Midtown · USUniversity of Maryland Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral sotalol, used in adults for sinus rhythm control, is initiated at 80 mg b.i.d. and titrated to a maximum safe dose. The US Food and Drug Administration recommends monitoring the corrected QT interval (QT

Indexed as

Research DesignAdministration, OralAgedAnti-Arrhythmia AgentsAtrial FibrillationComputer SimulationDose-Response Relationship, DrugDrug Administration ScheduleDrug MonitoringElectrocardiographyFemaleHeart RateHumansInfusions, IntravenousMaleMiddle AgedAnti-Arrhythmia AgentsSotalol

Identifiers

PMID31328888
PMCPMC6853149
OpenAlexW2962686269

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.