Article in Organic & biomolecular chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
9 authors.
Colwyn A HeadleyDepartment of Biological Chemistry and Pharmacology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA. villamena.1@osu.edu.ORCID 0000-0001-6041-7615
Claire N HoffmanDepartment of Biological Chemistry and Pharmacology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA. villamena.1@osu.edu.ORCID 0000-0002-6204-483X
Juliana M FreisenDepartment of Biological Chemistry and Pharmacology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA. villamena.1@osu.edu.
Yongbin HanDepartment of Biological Chemistry and Pharmacology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA. villamena.1@osu.edu.
Joseph M MacklinDepartment of Biological Chemistry and Pharmacology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA. villamena.1@osu.edu.
Jay L ZweierDavis Heart and Lung Research Institute, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Antal RockenbauerInstitute of Materials and Environmental Chemistry, Hungarian Academy of Sciences, and Department of Physics, Budapest University of Technology and Economics, Budapest, Hungary.ORCID 0000-0002-2865-1599
Jeff KuretDepartment of Biological Chemistry and Pharmacology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA. villamena.1@osu.edu.ORCID 0000-0002-8083-8406
Frederick A VillamenaDepartment of Biological Chemistry and Pharmacology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA. villamena.1@osu.edu.ORCID 0000-0002-7330-8431
Funding
Role of Cytoglobin in the Regulation of Vascular ToneR01HL131941 · NHLBI · OHIO STATE UNIVERSITY · PI JAY Louis ZWEIER · 2017 to 2026
$5.7M
Proton Electron Double Resonance Imaging (PEDRI) of Free RadicalsR01EB004900 · NIBIB · OHIO STATE UNIVERSITY · PI ZWEIER, JAY LOUIS · 2005 to 2008
$3.4M
Mechanisms of Nicotine Inhalation-Induced Cardiovascular DiseaseR01HL135648 · NHLBI · OHIO STATE UNIVERSITY · PI ZWEIER, JAY LOUIS · 2017 to 2021
$2.6M
Novel Spin Traps for Biological Free Radical DetectionR01HL081248 · NHLBI · OHIO STATE UNIVERSITY · PI VILLAMENA, FREDERICK A. · 2007 to 2010
$1.3M
Molecular Biophysics predoctoral training at The Ohio State UniversityT32GM118291 · NIGMS · OHIO STATE UNIVERSITY · PI BUNDSCHUH, RALF A, KURET, JEFF · 2017 to 2021
Membranous organelles are major endogenous sources of reactive oxygen and nitrogen species. When present at high levels, these species can cause macromolecular damage and disease. To better detect and scavenge free radical forms of the reactive species at their sources, we investigated whether nitrone spin traps could be selectively targeted to intracellular membranes using a bioorthogonal imaging approach. Electron paramagnetic resonance imaging demonstrated that the novel cyclic nitrone 5-dodecylcarbamoyl-5-N-dodecylacetamide-1-pyroline-N-oxide (diC
Indexed as
Density Functional TheoryFluorescenceOptical ImagingAcetamidesAnimalsCattleCells, CulturedElectron Spin Resonance SpectroscopyMolecular StructureAcetamides
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Membrane-specific spin trap, 5-dodecylcarbamoyl-5-N-dodecylacetamide-1-pyroline-N-oxide (diC · full record | OpenQuestion