Evidence map›Paper›PMID 31328158›Full record

ArticleScience advances2019

The regulatory B cell-mediated peripheral tolerance maintained by mast cell IL-5 suppresses oxazolone-induced contact hypersensitivity.

Hyuk Soon Kim, Min Bum Lee, Dajeong Lee, Keun Young Min, Jimo Koo, Hyun Woo Kim, Young Hwan Park, Su Jeong Kim, Masashi Ikutani, Satoshi Takaki and 2 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

  1. NFATc1 Abrogation in B Cells Ameliorates Contact Hypersensitivity Responses.International journal of molecular sciences · 2025
    Article
  2. IL-10Scientific reports · 2024
    Article
  3. Repeated exposure to eucalyptus wood smoke alters pulmonary gene and metabolic profiles in male Long-Evans rats.Toxicological sciences : an official journal of the Society of Toxicology · 2024
    Article
  4. Review
  5. IL-27-induced PD-L1Experimental & molecular medicine · 2024
    Article
  6. Breg-Mediated Immunoregulation in the Skin.International journal of molecular sciences · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Role of Innate Immunity in Allergic Contact Dermatitis: An Update.International journal of molecular sciences · 2023
    Review
  11. Article
  12. Article
  13. Roles of Mast Cells in Cutaneous Diseases.Frontiers in immunology · 2022
    Review
  14. Review
  15. Review
  16. Mast Cells in the Skin: Defenders of Integrity or Offenders in Inflammation?International journal of molecular sciences · 2021
    Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Hyuk Soon KimDepartment of Immunology, School of Medicine, Konkuk University, Chungju 27478, Korea.ORCID 0000-0002-0566-0142
Min Bum LeeDepartment of Immunology, School of Medicine, Konkuk University, Chungju 27478, Korea.ORCID 0000-0002-6873-1518
Dajeong LeeDepartment of Immunology, School of Medicine, Konkuk University, Chungju 27478, Korea.
Keun Young MinDepartment of Immunology, School of Medicine, Konkuk University, Chungju 27478, Korea.
Jimo KooDepartment of Immunology, School of Medicine, Konkuk University, Chungju 27478, Korea.
Hyun Woo KimDepartment of Immunology, School of Medicine, Konkuk University, Chungju 27478, Korea.
Young Hwan ParkDepartment of Immunology, School of Medicine, Konkuk University, Chungju 27478, Korea.
Su Jeong KimDepartment of Immunology, School of Medicine, Konkuk University, Chungju 27478, Korea.
Masashi IkutaniDepartment of Immune Regulation, The Research Center for Hepatitis and Immunology, Research Institute, National Center for Global Health and Medicine, Chiba 272-8516, Japan.
Satoshi TakakiDepartment of Immune Regulation, The Research Center for Hepatitis and Immunology, Research Institute, National Center for Global Health and Medicine, Chiba 272-8516, Japan.
Young Mi KimDepartment of Preventive Pharmacy, College of Pharmacy, Duksung Women's University, Seoul 01369, Korea.
Wahn Soo ChoiDepartment of Immunology, School of Medicine, Konkuk University, Chungju 27478, Korea.ORCID 0000-0002-0643-2395
Konkuk University · KRNational Center for Global Health and Medicine · JPDuksung Women's University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The function of regulatory immune cells in peripheral tissues is crucial to the onset and severity of various diseases. Interleukin-10 (IL-10)-producing regulatory B (IL-10

Indexed as

Peripheral ToleranceAnimalsB-Lymphocytes, RegulatoryB-Lymphocyte SubsetsCytokinesDermatitis, ContactDisease Models, AnimalFluorescent Antibody TechniqueImmunoglobulin IsotypesInterleukin-5MaleMast CellsMiceMice, KnockoutOxazoloneCytokinesImmunoglobulin IsotypesInterleukin-5Oxazolone

Identifiers

PMID31328158
PMCPMC6636983
OpenAlexW2960592492

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.