Evidence map›Paper›PMID 31327904›Full record

ArticleVeterinary world2019

Golden sea cucumber extract revives glucose transporter-4 and interleukin-6 protein level in diabetic mouse muscle.

Bambang Purwanto, Sundari Indah Wiyasihati, Putri Ayu Masyitha, Kristanti Wanito Wigati, Irfiansyah Irwadi

Open access · goldAbstract read
In one paragraph

Article in Veterinary world, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Clinical medicine insights. Endocrinology and diabetes · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Bambang PurwantoDepartment of Physiology, Faculty of Medicine, Universitas Airlangga, Indonesia.
Sundari Indah WiyasihatiDepartment of Physiology, Faculty of Medicine, Universitas Airlangga, Indonesia.
Putri Ayu MasyithaSchool of Medicine, Faculty of Medicine, Universitas Airlangga, Indonesia.
Kristanti Wanito WigatiDepartment of Physiology, Faculty of Medicine, Universitas Airlangga, Indonesia.
Irfiansyah IrwadiDepartment of Physiology, Faculty of Medicine, Universitas Airlangga, Indonesia.
Airlangga University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStreptozotocin (STZ)-induced free radical oxidant activity resulted in muscle wasting due to protein carbonyl (PC), glucose transporter-4 (Glut-4), and interleukin-6 (IL-6) protein alteration. Antioxidant ingredient in the golden sea cucumber extract was found in promising level to inhibit free radical activity.

aimThis study was aimed to investigate the effect of golden sea cucumber extract on PC, IL-6, and Glut-4 level of STZ-induced diabetes mouse. MATERIALS AND

methodsThis study was performed using mice, which were grouped into non-diabetes, diabetes, and diabetes-treated extract groups. The golden sea cucumber was extracted using 70% ethanol, which was administered by oral gavage twice a day for 5 consecutive days.

resultsThe extract reduced PC level and improved muscle Glut-4 and IL-6 protein level of diabetic mouse.

conclusionThe extract of golden sea cucumber revived muscle Glut-4 and IL-6 protein level in protection against muscle wasting.

Indexed as

diabetesglucose transporterinterleukinmuscle

Identifiers

PMID31327904
PMCPMC6584863
OpenAlexW2946570072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.