Evidence map›Paper›PMID 31327886›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2019

Reactive oxygen species explicit dosimetry to predict local tumor control for Photofrin-mediated photodynamic therapy.

Tianqi Sheng, Yi Hong Ong, Theresa M Busch, Timothy C Zhu

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tianqi ShengDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, United States.
Yi Hong OngDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, United States.
Theresa M BuschDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, United States.
Timothy C ZhuDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, United States.
California University of Pennsylvania · USUniversity of Pennsylvania · US

Funding

TUMOR HYPOXIA, PHOTOSENSITIZER, VASCULARITY AND PDTP01CA087971 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BUSCH, THERESA M, CENGEL, KEITH A · 2001 to 2019
$24.8M
Effects of Photodynamic Therapy on Tumor Oxygenation and Blood FlowR01CA085831 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BUSCH, THERESA M · 2001 to 2018
$4.7M
Image-guided treatment planning for pleural Photodynamic TherapyR01CA154562 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ZHU, TIMOTHY C. · 2012 to 2016
$1.6M
Development of Novel Fast GPU Monte Carlo and Active Photonics Simulation Software for Predicting PDT EfficacyR44CA183236 · NCI · SIMPHOTEK, INC. · PI CARY, JOHN R, POTASEK, MARY · 2016 to 2017
$1.5M
NCI NIH HHS P01 CA087971NCI NIH HHS R01 CA085831NCI NIH HHS R01 CA154562NCI NIH HHS R44 CA183236
6 · The paper itself

Abstract

Although photodynamic therapy (PDT) is an established modality for cancer treatment, current dosimetric quantities, such as light fluence and PDT dose, do not account for the differences in PDT oxygen consumption for different fluence rates (

Indexed as

explicit PDT dosimetrymacroscopic singlet oxygen modelphotodynamic therapyPhotofrin- mediated PDT

Identifiers

PMID31327886
PMCPMC6639794
OpenAlexW2921413324

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.