Evidence map›Paper›PMID 31327864›Full record

ArticleThe Kobe journal of medical sciences2019

Red LED Light Is Influenced by IL-6 to Promote the Migration Ability of Oral Squamous Cell Carcinoma Cell Line.

Kenji Matsuo, Hiroaki Suzuki, Nanae Yatagai, Yui Enomoto, Midori Kitayama, Manabu Shigeoka, Akira Kimoto, Kosuke Matsumoto, Takahide Komori

Abstract read
In one paragraph

Article in The Kobe journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kenji MatsuoDepartment of Oral Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Hiroaki SuzukiDepartment of Oral Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Nanae YatagaiDepartment of Oral Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Yui EnomotoDepartment of Oral Maxillofacial Surgery, Kakogawa Central City Hospital, Kakogawa, Japan.
Midori KitayamaDepartment of Oral Maxillofacial Surgery, Kobe Minimally invasive Cancer Center, Kobe, Japan.
Manabu ShigeokaDepartment of Oral Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Akira KimotoDepartment of Oral Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Kosuke MatsumotoDepartment of Oral Maxillofacial Surgery, Japan Community Health care Organization Kobe Central Hospital, Kobe, Japan.
Takahide KomoriDepartment of Oral Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe purpose of this study was to search for the influence of red LED light of oral squamous cell carcinoma cells (OSCC) Material & Methods: HSC-3 was irradiated with red LED light (630 nm/3 J). Proliferative capacity was analyzed using WST-1. Transwell migration assay, real-time PCR, and ELISA method were also used to analyze migratory ability.

conclusionsHSC-3 cells irradiated with red LED light showed increased migration ability. Interestingly, we clarified that the expression of Interleukin-6 (IL-6), which promotes the migratory ability of cancer cells, is induced.

Indexed as

LightCell Line, TumorCell MovementHumansInterleukin-6Mouth NeoplasmsSquamous Cell Carcinoma of Head and NeckInterleukin-6IL-6LEDLow-level laser therapymigrationOral squamous cell carcinoma

Identifiers

PMID31327864
PMCPMC6668650

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.