Evidence map›Paper›PMID 31327570›Full record

ArticleInternational journal of hygiene and environmental health2019

Benefits of cooperation among large-scale cohort studies and human biomonitoring projects in environmental health research: An exercise in blood lead analysis of the Environment and Child Health International Birth Cohort Group.

Shoji F Nakayama, Carolina Espina, Michihiro Kamijima, Per Magnus, Marie-Aline Charles, Jun Zhang, Birgit Wolz, André Conrad, Aline Murawski, Miyuki Iwai-Shimada and 7 more

Abstract readComparative Study
In one paragraph

Article in International journal of hygiene and environmental health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. The Heartbeat of Global Health.European journal of cardiovascular nursing · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. An Inventory of European Birth Cohorts.International journal of environmental research and public health · 2020
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Shoji F NakayamaJapan Environment and Children's Study Programme Office, National Institute for Environmental Studies, Tsukuba, Japan. Electronic address: fabre@nies.go.jp.
Carolina EspinaInternational Agency for Research on Cancer (IARC), Section of Environment and Radiation, Lyon, France.
Michihiro KamijimaNagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Per MagnusCentre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
Marie-Aline CharlesIned, Inserm, EFS, Elfe Joint Unit, Paris, France.
Jun ZhangMinistry of Education - Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Birgit WolzFederal Ministry for the Environment, Nature Conservation and Nuclear Safety, Bonn, Germany.
André ConradGerman Environment Agency, Section Toxicology, Health Related Monitoring, Berlin, Germany.
Aline MurawskiGerman Environment Agency, Section Toxicology, Health Related Monitoring, Berlin, Germany.
Miyuki Iwai-ShimadaJapan Environment and Children's Study Programme Office, National Institute for Environmental Studies, Tsukuba, Japan.
Cécile ZarosIned, Inserm, EFS, Elfe Joint Unit, Paris, France.
Ida Henriette CaspersenDivision of Infection Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.
Marike Kolossa-GehringGerman Environment Agency, Section Toxicology, Health Related Monitoring, Berlin, Germany.
Helle Margrete MeltzerDivision of Infection Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.
Sjurdur F OlsenCentre for Fetal Programming, Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, 02115, USA.
Ruth A EtzelMilken Institute School of Public Health, The George Washington University, Washington, DC, USA.
Joachim SchüzInternational Agency for Research on Cancer (IARC), Section of Environment and Radiation, Lyon, France.

Funding

Gene-Environment Interactions in an Autism Birth CohortU01NS047537 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LIPKIN, W. IAN · 2003 to 2013
$27.0M
NIEHS NIH HHS N01 ES075558NINDS NIH HHS U01 NS047537World Health Organization 001
6 · The paper itself

Abstract

A number of prospective cohort studies are ongoing worldwide to investigate the impact of foetal and neonatal exposures to chemical substances on child health. To assess multiple exposure (mixture) effects and low prevalence health outcomes it is useful to pool data from several studies and conduct mega-data-analysis. To discuss a path towards data harmonization, representatives from several large-scale birth cohort studies and a biomonitoring programme formed a collaborative group, the Environment and Child Health International Birth Cohort Group (ECHIBCG). In this study, an intra-laboratory trial was performed to harmonize existing blood lead measurements within the groups' studies. Then, decentralized analyses were conducted in individual countries' laboratories to evaluate blood lead levels (BLL) in each study. The measurements of pooled BLL samples in French, German and three Japanese laboratories resulted in an overall mean blood lead concentration of 8.66 μg l

Indexed as

Biological MonitoringInternational CooperationAdultCohort StudiesEnvironmental HealthEnvironmental PollutantsFemaleFetal BloodHumansInfant, NewbornLaboratoriesLeadMaleMothersEnvironmental PollutantsLeadBirth cohortChildEnvironmentHarmonizationHBMHuman biomonitoringLeadLead (PubChem CID: 5352425)Pregnancy

Identifiers

PMID31327570
PMCPMC6732228

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.