Evidence map›Paper›PMID 31327218›Full record

ReviewJournal of neurogastroenterology and motility2019

Second Asian Consensus on Irritable Bowel Syndrome.

Kok Ann Gwee, Sutep Gonlachanvit, Uday C Ghoshal, Andrew S B Chua, Hiroto Miwa, Justin Wu, Young-Tae Bak, Oh Young Lee, Ching-Liang Lu, Hyojin Park and 11 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of neurogastroenterology and motility, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07425145 (Transcutaneous Electrical Acustimulation), which is not on this map. Cited by 60 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07425145 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Transcutaneous Electrical Acustimulation (TEA) for Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D): A Multicenter, Randomized, Sham-Controlled Trial

TypeinterventionalSponsorFirst People's Hospital of FoshanRan2026 to 2028Enrolled200ConditionsIBS, Diarrhea PredominantArmsPortable stimulator
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Kok Ann GweeDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, and Gleneagles Hospital, Singapore.
Sutep GonlachanvitCenter of Excellence on Neurogastroenterology and Motility, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Uday C GhoshalDepartment of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Andrew S B ChuaGastro Centre, Ipoh, Malaysia.
Hiroto Miwa5 Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Mukogawa-cho, Nishinomiya, Hyogo, Japan.
Justin WuDepartment of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, Hong Kong.
Young-Tae BakDepartment of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Oh Young LeeDepartment of Gastroenterology, College of Medicine, Hanyang University, Seoul, Korea.
Ching-Liang LuEndoscopy Center for Diagnosis and Treatment, Taipei Veterans General Hospital, Taipei, Taiwan.
Hyojin ParkDivision of Gastroenterology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Minhu ChenDepartment of Gastroenterology and Hepatology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Ari F SyamDivision of Gastroenterology, Departement of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Philip AbrahamDivision of Gastroenterology, P D Hinduja Hospital, Mumbai, India.
Jose SollanoDepartment of Internal Medicine, Division of Gastroenterology, University of Santo Tomas, Manila, Philippine.
Chi-Sen ChangTaichung Veterans General Hospital, Taiwan Boulevard, Taichung City, Taiwan.
Hidekazu SuzukiDepartment of Gastroenterology and Hepatology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Xiucai FangDepartment of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Shin FukudoDepartment of Behavioral Medicine, Tohoku University Graduate School of Medicine, Aoba Sendai, Japan.
Myung-Gyu ChoiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.
Xiaohua HouUnion Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Michio HongoDepartment of Medicine, Kurokawa General Hospital, Kurokawa, Miyagi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThere has been major progress in our understanding of the irritable bowel syndrome (IBS), and novel treatment classes have emerged. The Rome IV guidelines were published in 2016 and together with the growing body of Asian data on IBS, we felt it is timely to update the Asian IBS Consensus.

methodsKey opinion leaders from Asian countries were organized into 4 teams to review 4 themes: symptoms and epidemiology, pathophysiology, diagnosis and investigations, and lifestyle modifications and treatments. The consensus development process was carried out by using a modified Delphi method.

resultsThirty-seven statements were developed. Asian data substantiate the current global viewpoint that IBS is a disorder of gut-brain interaction. Socio-cultural and environmental factors in Asia appear to influence the greater overlap between IBS and upper gastrointestinal symptoms. New classes of treatments comprising low fermentable oligo-, di-, monosacharides, and polyols diet, probiotics, non-absorbable antibiotics, and secretagogues have good evidence base for their efficacy.

conclusionsOur consensus is that all patients with functional gastrointestinal disorders should be evaluated comprehensively with a view to holistic management. Physicians should be encouraged to take a positive attitude to the treatment outcomes for IBS patients.

Indexed as

AsiaConstipationDiarrheaIntestinesIrritable bowel syndrome

Identifiers

PMID31327218
PMCPMC6657923

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.