Evidence map›Paper›PMID 31327092›Full record

ArticleClinical and experimental nephrology2019

Prevalence of chronic kidney disease among HIV-1-infected patients receiving a combination antiretroviral therapy.

Leonardo Calza, Michele Sachs, Vincenzo Colangeli, Marco Borderi, Bianca Granozzi, Pietro Malosso, Giorgia Comai, Valeria Corradetti, Gaetano La Manna, Pierluigi Viale

Abstract read
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In one paragraph

Article in Clinical and experimental nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Leonardo CalzaUnit of Infectious Diseases, Department of Medical and Surgical Sciences, S. Orsola Hospital, "Alma Mater Studiorum" University of Bologna, via G. Massarenti 11, 40138, Bologna, Italy. leonardo.calza@unibo.it.ORCID http://orcid.org/0000-0002-1895-1504
Michele SachsUnit of Infectious Diseases, Department of Medical and Surgical Sciences, S. Orsola Hospital, "Alma Mater Studiorum" University of Bologna, via G. Massarenti 11, 40138, Bologna, Italy.
Vincenzo ColangeliUnit of Infectious Diseases, Department of Medical and Surgical Sciences, S. Orsola Hospital, "Alma Mater Studiorum" University of Bologna, via G. Massarenti 11, 40138, Bologna, Italy.
Marco BorderiUnit of Infectious Diseases, Department of Medical and Surgical Sciences, S. Orsola Hospital, "Alma Mater Studiorum" University of Bologna, via G. Massarenti 11, 40138, Bologna, Italy.
Bianca GranozziUnit of Infectious Diseases, Department of Medical and Surgical Sciences, S. Orsola Hospital, "Alma Mater Studiorum" University of Bologna, via G. Massarenti 11, 40138, Bologna, Italy.
Pietro MalossoUnit of Infectious Diseases, Department of Medical and Surgical Sciences, S. Orsola Hospital, "Alma Mater Studiorum" University of Bologna, via G. Massarenti 11, 40138, Bologna, Italy.
Giorgia ComaiUnit of Nephrology, Department of Medical and Surgical Sciences, S.Orsola Hospital, University of Bologna, Bologna, Italy.
Valeria CorradettiUnit of Nephrology, Department of Medical and Surgical Sciences, S.Orsola Hospital, University of Bologna, Bologna, Italy.
Gaetano La MannaUnit of Nephrology, Department of Medical and Surgical Sciences, S.Orsola Hospital, University of Bologna, Bologna, Italy.
Pierluigi VialeUnit of Infectious Diseases, Department of Medical and Surgical Sciences, S. Orsola Hospital, "Alma Mater Studiorum" University of Bologna, via G. Massarenti 11, 40138, Bologna, Italy.
University of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) has become one of the most frequent non-infectious comorbidities in the aging HIV-infected population on long-standing combination antiretroviral therapy (cART).

methodsWe conducted a retrospective, cross-sectional study including HIV-infected adult patients attending our HIV outpatient clinic during the years 2017 and 2018 to assess prevalence and associated risk factors of CKD. Estimated glomerular filtration rate (eGFR) was measured by Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) equation. CKD was diagnosed and classified according to the National Kidney Foundation guidelines. Logistic regression was employed to identify factors associated with CKD.

resultsWe enrolled 2339 HIV-infected patients (91% were Caucasian) with a mean age of 45.3 years and a mean current CD4 lymphocyte count of 531 cells/mm

conclusionThere is a significant prevalence of CKD among HIV-infected persons in association with both traditional and HIV-specific risk factors, requiring a careful periodic monitoring of renal function in these patients.

Indexed as

HIV-1AbacavirAdultAge FactorsAlbuminuriaAnti-HIV AgentsCD4 Lymphocyte CountCross-Sectional StudiesDiabetes MellitusDideoxynucleosidesDrug Therapy, CombinationFemaleGlomerular Filtration RateHIV InfectionsHumansHypertensionAbacavirAnti-HIV AgentsDideoxynucleosidesIntegrase InhibitorsRitonavirTenofovirAlbuminuriaAntiretroviral drugsGlomerular filtration rateProteinuriaRenal dysfunction

Identifiers

PMID31327092
OpenAlexW2963233146

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.