Evidence map›Paper›PMID 31327032›Full record

Observational studyInternational urogynecology journal2019

The effect of the first vaginal birth on pelvic floor anatomy and dysfunction.

Iva Urbankova, Klara Grohregin, Jiri Hanacek, Michal Krcmar, Jaroslav Feyereisl, Jan Deprest, Ladislav Krofta

Registry-linked trialOpen access · hybridAbstract readObservational Study
In one paragraph

Observational study in International urogynecology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05530681 (Correlation Pelvic Floor Function and Ultrasound Findings One Year After Childbirth), which is not on this map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05530681 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Correlation Pelvic Floor Function and Ultrasound Findings One Year After Childbirth

TypeinterventionalSponsorUniversitaire Ziekenhuizen KU LeuvenRan2022 to 2025Enrolled320ConditionsPelvic Floor Disorders, Obstetric Trauma, Urinary Incontinence, Anal IncontinenceArmsQuestionnaire, Pelvic floor ultrasound
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 93 citations in OpenAlex.

  1. Pooled it
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  14. Reducing pelvic floor injury by induction of labor.International urogynecology journal · 2022
    Article
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  16. Observational
  17. Sexual function in primiparous women: a prospective study.International urogynecology journal · 2022
    Article
  18. Pelvic Organ Prolapse in Perimenopausal and Menopausal Women.Journal of obstetrics and gynaecology of India · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Iva UrbankovaInstitute for the Care of Mother and Child and Third Faculty of Medicine, Charles University, Podolske nabrezi 157, 14700, Prague, Czech Republic.
Klara GrohreginInstitute for the Care of Mother and Child and Third Faculty of Medicine, Charles University, Podolske nabrezi 157, 14700, Prague, Czech Republic.
Jiri HanacekInstitute for the Care of Mother and Child and Third Faculty of Medicine, Charles University, Podolske nabrezi 157, 14700, Prague, Czech Republic.
Michal KrcmarInstitute for the Care of Mother and Child and Third Faculty of Medicine, Charles University, Podolske nabrezi 157, 14700, Prague, Czech Republic.
Jaroslav FeyereislInstitute for the Care of Mother and Child and Third Faculty of Medicine, Charles University, Podolske nabrezi 157, 14700, Prague, Czech Republic.
Jan DeprestDepartment of Development and Regeneration, Organ systems cluster, Group Biomedical Sciences, and Pelvic Floor Unit, University Hospitals KU Leuven, Leuven, Belgium.
Ladislav KroftaInstitute for the Care of Mother and Child and Third Faculty of Medicine, Charles University, Podolske nabrezi 157, 14700, Prague, Czech Republic. ladislav.krofta@upmd.eu.ORCID 0000-0002-4372-3394
Charles University · CZKU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisFirst vaginal delivery severely interferes with pelvic floor anatomy and function. This study determines maternal and pregnancy-related risk factors for pelvic floor dysfunction (PFD), including urinary incontinence (UI), urgency, anal incontinence (AI), pelvic organ prolapse (POP) and levator ani muscle (LAM) avulsion.

methodsThis is a single-centre prospective observational cohort study on healthy women in their first singleton pregnancy. All underwent clinical and 3D transperineal ultrasound examination at 6 weeks and 12 months postpartum. Objective outcomes were POP-Q and presence or absence of LAM trauma. Functional outcomes were measured by the ICIQ-SF and PISQ 12. Multivariate regression was performed to determine birth and maternal habitus-related risk factors for UI, urgency, AI, dyspareunia, LAM avulsion and ballooning.

resultsNine hundred eighty-seven women were included. Risk factors for UI were maternal age per year of age (OR: 1.09; 95% CI: 1.04-1.13; p = 0.0001) and BMI before pregnancy (OR: 1.08; 95% CI: 1.04-1.13; p = 0.001); for POP stage II+ maternal age (OR: 1.08; 95% CI: 1.08-1.14; p = 0.005). Avulsion was more likely after forceps (OR: 3.22; 95% CI:1.54-8.22; p = 0.015) but less likely after epidural analgesia (OR: 0.58; 95% CI: 0.37-0.90; p = 0.015) and grade I perineal rupture (OR: 0.50; 95% CI: 0.29-0.85; p = 0.012). Ballooning was more likely at increased maternal age (OR: 1.08; 95% CI: 1.02-1.13; p = 0.005), epidural (OR: 1.64; 95% CI: 1.06-2.55; p = 0.027) and grade I perineal rupture (OR: 1.79; 95% CI: 1.10-2.90; p = 0.018).

conclusionThough maternal characteristics at birth such as age or BMI increase the risk of PFD, labour and birth factors play a similarly important role. The most critical risk factor for MLA avulsion was forceps delivery, while an epidural had a protective effect.

Indexed as

AdultDelivery, ObstetricFecal IncontinenceFemaleHumansParityParturitionPelvic Floor DisordersPregnancyProspective StudiesUrinary IncontinenceBMIForcepsIncontinenceMaternal agePelvic organ prolapse

Identifiers

PMID31327032
PMCPMC6795623
OpenAlexW2963802214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.