Evidence map›Paper›PMID 31326965›Full record

Observational studyAging2019

Shortening telomere is associated with subclinical atherosclerosis biomarker in omnivorous but not in vegetarian healthy men.

Naiara Cinegaglia, Luiza Antoniazzi, Daniela Rosa, Debora Miranda, Julio Acosta-Navarro, Luiz Bortolotto, Valeria Hong, Valeria Sandrim

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Naiara CinegagliaInstitute of Bioscience, São Paulo State University - IBB/UNESP, Botucatu, São Paulo, Brazil.
Luiza AntoniazziHeart Institute (InCor), Medical School, University of São Paulo, São Paulo, Brazil.
Daniela RosaLaboratory of Molecular Medicine, Medical School, Federal University of Minas Gerais, UFMG, Minas Gerais, Brazil.
Debora MirandaLaboratory of Molecular Medicine, Medical School, Federal University of Minas Gerais, UFMG, Minas Gerais, Brazil.
Julio Acosta-NavarroHeart Institute (InCor), Medical School, University of São Paulo, São Paulo, Brazil.
Luiz BortolottoHeart Institute (InCor), Medical School, University of São Paulo, São Paulo, Brazil.
Valeria HongHeart Institute (InCor), Medical School, University of São Paulo, São Paulo, Brazil.
Valeria SandrimInstitute of Bioscience, São Paulo State University - IBB/UNESP, Botucatu, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Telomere length is considered to be a biomarker of biological aging and age-related disease. There are few studies that have evaluated the association between telomere length and diet, and none of them have evaluated the impact of a vegetarian diet on telomere length and its correlation with cardiovascular biomarkers in apparently healthy subjects. Therefore, our objectives were to evaluate leukocyte telomere length (LTL) in vegetarians and omnivorous subjects and its association with classical cardiovascular risk biomarkers. From the total of 745 participants initially recruited, 44 omnivorous and 44 vegetarian men apparently healthy were selected for this study and LTL was measured in 39 omnivorous and 41 vegetarians by Real-Time Quantitative PCR reaction. Although telomere length was not different between omnivorous and vegetarians, we found a strong negative correlation between LTL and IMT (intima-media thickness) in omnivorous, but not in vegetarian group. In addition, omnivorous who were classified with short telomere length had higher carotid IMT compared to vegetarians. Our data suggest that telomere length can be a marker of subclinical atherosclerosis in the omnivorous group.

Indexed as

Carotid Intima-Media ThicknessTelomere ShorteningVegetariansAtherosclerosisCross-Sectional StudiesDiet, VegetarianHumansMaleMiddle Agedcardiovascularcarotid intima-media thicknesstelomere lengthvegetarian

Identifiers

PMID31326965
PMCPMC6682516

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.