Evidence map›Paper›PMID 31326503›Full record

Observational studyJournal of pain and symptom management2019

Outcomes of Palliative Care Consultations for Hospitalized Patients With Liver Disease.

Nneka N Ufere, David L O'Riordan, Kara E Bischoff, Angela K Marks, Nwamaka Eneanya, Raymond T Chung, Vicki Jackson, Steven Z Pantilat, Areej El-Jawahri

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Journal of pain and symptom management, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Review
  5. Article
  6. Quality of end-of-life care with non-malignant liver disease: Analysis of the VOICES National Survey of Bereaved People.Liver international : official journal of the International Association for the Study of the Liver · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Nneka N UfereLiver Center and Gastrointestinal Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address: nneka.ufere@mgh.harvard.edu.
David L O'RiordanDivision of Palliative Medicine, Department of Medicine, University of California, San Francisco, California, USA.
Kara E BischoffDivision of Palliative Medicine, Department of Medicine, University of California, San Francisco, California, USA.
Angela K MarksDivision of Palliative Medicine, Department of Medicine, University of California, San Francisco, California, USA.
Nwamaka EneanyaPalliative and Advanced Illness Research Center, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Raymond T ChungLiver Center and Gastrointestinal Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Vicki JacksonDivision of Palliative Care and Geriatric Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Steven Z PantilatDivision of Palliative Medicine, Department of Medicine, University of California, San Francisco, California, USA.
Areej El-JawahriDivision of Hematology and Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Harvard University · USUniversity of California, San Francisco · USUniversity of Pennsylvania · US

Funding

RESEARCH TRAINING IN DIGESTIVE DISEASES AND NUTRITIONT32DK007191 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1986 to 2026
$14.6M
Patient-Oriented Research on Hepatitis in Special PopulationsK24DK078772 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHUNG, RAYMOND T · 2007 to 2016
$1.6M
Integrating Conservative Kidney Management Options and Advance Care Planning Into a Pre-Dialysis Educational ProgramK23DK114526 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI ENEANYA, NWAMAKA · 2017 to 2021
$819k
NIDDK NIH HHS K23 DK114526NIDDK NIH HHS K24 DK078772NIDDK NIH HHS T32 DK007191
6 · The paper itself

Abstract

contextAlthough palliative care (PC) has been shown to improve symptoms and end-of-life (EOL) care for patients with cancer, data are lacking on the patterns of use and outcomes of PC consultations for hospitalized patients with liver disease.

objectivesWe sought to characterize the patterns of use and outcomes of PC consultations for hospitalized patients with liver disease compared with patients with cancer.

methodsWe conducted an observational study using data from the Palliative Care Quality Network (PCQN). The PCQN contains prospectively collected data on 135,197 hospitalized patients receiving PC consultations at 88 PCQN sites between January 2013 and December 2017. The PCQN data set includes patient demographics, processes of care, and patient-level clinical outcomes.

resultsThe cohort included 44,933 patients, of whom 4402 (9.8%) had liver disease and 40,531 (90.2%) had cancer. Patients with liver disease were younger (58.9 years vs. 65.2 years, P < 0.0001) and had higher in-hospital mortality (28% vs. 16.8%, P < 0.0001). Patients with liver disease were more likely to receive PC consultations to address goals of care (81.7% vs. 67.9%, P < 0.0001) as opposed to pain management (10.9% vs. 34.9%, P < 0.0001). Both groups had similar rates of symptom improvement and change in resuscitation preferences after PC consultation.

conclusionHospitalized patients with liver disease were more likely to have a PC referral to address goals of care compared with those with cancer and were more likely to die in the hospital. Despite late PC consultations, patients with liver disease experienced improvement in symptoms and clarification of their goals of care, similar to those with cancer.

Indexed as

Liver DiseasesNeoplasmsPalliative CarePatient Care PlanningReferral and ConsultationTerminal CareAgedDatabases, FactualFemaleHumansMaleMiddle Agedadvance care planningcancercirrhosisPalliative caresymptom management

Identifiers

PMID31326503
PMCPMC6823143
OpenAlexW2963023665

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.