Evidence map›Paper›PMID 31325316›Full record

ArticleInternational journal of cancer2020

Human papillomavirus genotypes in women with invasive cervical cancer with and without human immunodeficiency virus infection in Botswana.

Leabaneng Tawe, Emily MacDuffie, Mohan Narasimhamurthy, Qiao Wang, Simani Gaseitsiwe, Sikhulile Moyo, Ishmael Kasvosve, Sanghyuk S Shin, Nicola M Zetola, Giacomo M Paganotti and 1 more

Open access · greenAbstract read
In one paragraph

Article in International journal of cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Leabaneng TaweDepartment of Medical Laboratory Sciences, Faculty of Health Sciences, University of Botswana, Gaborone, Botswana.
Emily MacDuffieWarren Alpert Medical School of Brown University, Providence, RI.
Mohan NarasimhamurthyDepartment of Pathology, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Qiao WangSue & Bill Gross School of Nursing, University of California Irvine, Irvine, CA.
Simani GaseitsiweBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Sikhulile MoyoBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Ishmael KasvosveDepartment of Medical Laboratory Sciences, Faculty of Health Sciences, University of Botswana, Gaborone, Botswana.
Sanghyuk S ShinSue & Bill Gross School of Nursing, University of California Irvine, Irvine, CA.
Nicola M ZetolaBotswana-University of Pennsylvania Partnership, Gaborone, Botswana.
Giacomo M PaganottiBotswana-University of Pennsylvania Partnership, Gaborone, Botswana.
Surbhi GroverBotswana-University of Pennsylvania Partnership, Gaborone, Botswana.ORCID 0000-0001-7443-5937
University of Botswana · BWMassachusetts Department of Public Health · USUniversity of California, Irvine · USBrown University · US

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ROBERT GROSS · 1999 to 2026
$78.6M
Shared Resources CoreU54CA190158 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ROBERTSON, ERLE S. · 2014 to 2023
$4.2M
Prognostic value of quantitative HPV viral load in determining cervical cancer treatment response and recurrenceK08CA230170 · NCI · UNIVERSITY OF PENNSYLVANIA · PI GROVER, SURBHI · 2019 to 2023
$1.4M
Growth Trends and Mortality Risks Among HIV-exposed Infants in BotswanaK23HD070774 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI POWIS, KATHLEEN · 2012 to 2016
$686k
The Effect of Mixed-strain Mycobacterium tuberculosis Infections on TB Treatment Outcomes in Botswana: A Retrospective Cohort Study.K01AI118559 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SHIN, SANGHYUK SAM · 2015 to 2019
$670k
Risk Factors for the Development of Lactic Acidosis and Pancreatitis Among HAART-K23AI073141 · NIAID · VANDERBILT UNIVERSITY · PI WESTER, C. WILLIAM · 2007 to 2011
$643k
Conquer Cancer Foundation Young Investigator Award, and Penn Center for AIDS Research 5-P30-AI-045008-17NCI NIH HHS K08 CA230170NCI NIH HHS U54 CA190158NIAID NIH HHS K01 AI118559NIAID NIH HHS K23 AI073141NIAID NIH HHS P30 AI045008Wellcome TrustWellcome Trust 107752/Z/15/Z
6 · The paper itself

Abstract

Cervical cancer remains a significant cause of morbidity and mortality in women worldwide and is the leading cause of cancer-related death in Botswana. It is well established that women with HIV have a higher risk of persistent HPV infection leading to cervical cancer. We assessed HPV prevalence and genotype distribution in 126 tissue specimens from confirmed invasive cervical cancer cases using Abbott real-time PCR assay. Overall, 88 (69.8%) women were HIV-infected. Fifty-seven (64.8%) of the HIV-infected women had a baseline CD4

Indexed as

Anti-HIV AgentsBotswanaCervix UteriCost of IllnessCross-Sectional StudiesDNA, ViralFemaleGenotypeHIV InfectionsHuman papillomavirus 16Human papillomavirus 18HumansMiddle AgedPapillomavirus InfectionsPapillomavirus VaccinesPrevalenceAnti-HIV AgentsDNA, ViralPapillomavirus VaccinesBotswanaHIVHPV-16HPV-18invasive cervical cancermultiple infections

Identifiers

PMID31325316
PMCPMC7055961
OpenAlexW2964093579

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.