Evidence map›Paper›PMID 31325088›Full record

ArticleJournal of biomolecular NMR2019

Assigning NMR spectra of RNA, peptides and small organic molecules using molecular network visualization software.

Jan Marchant, Michael F Summers, Bruce A Johnson

Abstract read
In one paragraph

Article in Journal of biomolecular NMR, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Application of NMR to Large RNAs.Journal of molecular biology · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jan MarchantDepartment of Chemistry and Biochemistry, University of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore, MD, 21250, USA.
Michael F SummersDepartment of Chemistry and Biochemistry, University of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore, MD, 21250, USA.
Bruce A JohnsonStructural Biology Initiative, CUNY Advanced Science Research Center, 85 St. Nicholas Terrace, New York, NY, 10031, USA. bruce.johnson@asrc.cuny.edu.ORCID http://orcid.org/0000-0001-8445-5368

Funding

The Center for HIV RNA Studies (CRNA)U54AI150470 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHIU, WAH · 2019 to 2021
$15.1M
The Center for HIV RNA Studies (CRNA)U54GM103297 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TELESNITSKY, ALICE · 2017 to 2018
$10.2M
NMR STUDIES OF RETROVIRAL NUCLEOCAPSID PROTEINSR01GM042561 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SUMMERS, MICHAEL FINLEY · 1994 to 2019
$9.4M
NMRFx: An Integrated software suite for macromolecular NMR analysisR01GM123012 · NIGMS · ADVANCED SCIENCE RESEARCH CENTER · PI JOHNSON, BRUCE A · 2017 to 2025
$2.6M
NMR STUDIES OF RETROVIRAL NUCLEIC ACID BINDING PROTEINSR29GM042561 · NIGMS · UNIVERSITY OF MARYLAND BALT CO CAMPUS · PI SUMMERS, MICHAEL F. · 1989 to 1993
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NIAID NIH HHS U54 AI150470NIGMS NIH HHS GM 42561NIGMS NIH HHS R01 GM042561NIGMS NIH HHS R01 GM 123012NIGMS NIH HHS R01 GM123012NIGMS NIH HHS U54 GM 103297NIGMS NIH HHS U54 GM103297
6 · The paper itself

Abstract

NMR assignment typically involves analysis of peaks across multiple NMR spectra. Chemical shifts of peaks are measured before being assigned to atoms using a variety of methods. These approaches quickly become complicated by overlap, ambiguity, and the complexity of correlating assignments among multiple spectra. Here we propose an alternative approach in which a network of linked peak-boxes is generated at the predicted positions of peaks across all spectra. These peak-boxes correlate known relationships and can be matched to the observed spectra. The method is illustrated with RNA, but a variety of molecular types should be readily tractable with this approach.

Indexed as

SoftwareModels, MolecularNuclear Magnetic Resonance, BiomolecularOrganic ChemicalsPeptidesRNAOrganic ChemicalsPeptidesRNAChemical shift assignmentPeptidesPredictionRNASoftware

Identifiers

PMID31325088
PMCPMC6859155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.