Evidence map›Paper›PMID 31324937›Full record

ReviewEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2020

A nationwide fluidics biobank of polytraumatized patients: implemented by the Network "Trauma Research" (NTF) as an expansion to the TraumaRegister DGU

Borna Relja, Markus Huber-Lang, Martijn van Griensven, Frank Hildebrand, Marc Maegele, Ulrike Nienaber, Daniel P Brucker, Ramona Sturm, Ingo Marzi

Abstract readReview
In one paragraph

Review in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Extension of the fluidics NTF-Biobank of polytraumatized patients with extracellular vesicles: improved vesicle preservation through local processing.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  2. Article
  3. Article
  4. Physiologic impact of inflammation in the polytrauma patient.OTA international : the open access journal of orthopaedic trauma · 2025
    Article
  5. Influence of hemolysis, lipemia and bilirubin on biobank sample quality- origin and interference in the use for extracellular vesicle (EV) and MiRNA analyses.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
  6. Article
  7. Article
  8. Pre-Hospital Stroke Care beyond the MSU.Current neurology and neuroscience reports · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Focus on "The German TraumaRegister DGUEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Borna ReljaDepartment of Trauma, Hand and Reconstructive, Surgery, University Hospital Frankfurt, Goethe-University, 60590, Frankfurt, Germany. info@bornarelja.com.
Markus Huber-LangInstitute of Clinical- and Experimental Trauma-Immunology, University of Ulm, Ulm, Germany.
Martijn van GriensvenExperimental Trauma Surgery, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
Frank HildebrandDepartment of Orthopaedic Trauma, RWTH Aachen University, Aachen, Germany.
Marc MaegeleDepartment for Traumatology and Orthopedic Surgery, Cologne-Merheim Medical Centre, University of Witten/Herdecke, Cologne, Germany.
Ulrike NienaberAUC-Academy for Trauma Surgery, Cologne, Germany.
Daniel P BruckerUniversity Cancer Center Frankfurt and Interdisciplinary Biomaterial Bank and Database Frankfurt, University Hospital Frankfurt, Goethe University, Frankfurt, Germany.
Ramona SturmDepartment of Trauma, Hand and Reconstructive, Surgery, University Hospital Frankfurt, Goethe-University, 60590, Frankfurt, Germany.
Ingo MarziDepartment of Trauma, Hand and Reconstructive, Surgery, University Hospital Frankfurt, Goethe-University, 60590, Frankfurt, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To decrypt the complexity of the posttraumatic immune responses and to potentially identify novel research pathways for exploration, large-scale multi-center projects including not only in vivo and in vitro modeling, but also temporal sample and material collection along with clinical data capture from multiply injured patients is of utmost importance. To meet this gap, a nationwide biobank for fluidic samples from polytraumatized patients was initiated in 2013 by the task force Network "Trauma Research" (Netzwerk Traumaforschung, NTF) of the German Trauma Society (Deutsche Gesellschaft für Unfallchirurgie e.V., DGU). The NTF-Biobank completes the clinical NTF-Biobank Database and complements the TR-DGU with temporal biological samples from multiply injured patients. The concept behind the idea of the NTF-Biobank was to create a robust interface for meaningful innovative basic, translational and clinical research. For the first time, an integrated platform to prospectively evaluate and monitor candidate biomarkers and/or potential therapeutic targets in biological specimens of quality-controlled and documented patients is introduced, allowing reduction in variability of measurements with high impact due to its large sample size. Thus, the project was introduced to systemically evaluate and monitor multiply injured patients for their (patho-)physiological sequalae together with their clinical treatment strategies applied for overall outcome improval.

Indexed as

Biological Specimen BanksBody FluidsRegistriesGermanyHumansMultiple TraumaTranslational Research, BiomedicalBiobankConsortiumNTFRegistryResearchTrauma

Identifiers

PMID31324937
PMCPMC7280175

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.