Evidence map›Paper›PMID 31324861›Full record

ArticleScientific reports2019

SMAC, a computational system to link literature, biomedical and expression data.

Stefano Pirrò, Emanuela Gadaleta, Andrea Galgani, Vittorio Colizzi, Claude Chelala

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stefano PirròBioinformatics Unit, Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University London, London, EC1M 6BQ, UK. s.pirro@qmul.ac.uk.ORCID http://orcid.org/0000-0002-8601-722X
Emanuela GadaletaBioinformatics Unit, Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University London, London, EC1M 6BQ, UK.
Andrea GalganiInterdepartmental Centre for Animal Technology, University of Rome Tor Vergata, Rome, Italy.
Vittorio ColizziDepartment of Biology, University of Rome Tor Vergata, Rome, Italy.
Claude ChelalaBioinformatics Unit, Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University London, London, EC1M 6BQ, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-throughput technologies have produced a large amount of experimental and biomedical data creating an urgent need for comprehensive and automated mining approaches. To meet this need, we developed SMAC (SMart Automatic Classification method): a tool to extract, prioritise, integrate and analyse biomedical and molecular data according to user-defined terms. The robust ranking step performed on Medical Subject Headings (MeSH) ensures that papers are prioritised based on specific user requirements. SMAC then retrieves any related molecular data from the Gene Expression Omnibus and performs a wide range of bioinformatics analyses to extract biological insights. These features make SMAC a robust tool to explore the literature around any biomedical topic. SMAC can easily be customised/expanded and is distributed as a Docker container ( https://hub.docker.com/r/hfx320/smac ) ready-to-use on Windows, Mac and Linux OS. SMAC's functionalities have already been adapted and integrated into the Breast Cancer Now Tissue Bank bioinformatics platform and the Pancreatic Expression Database.

Indexed as

Data MiningGene ExpressionInformation Storage and RetrievalPeriodicals as TopicComputational BiologyComputer SystemsHumansInformation SystemsMedical Subject HeadingsMetadataSoftware

Identifiers

PMID31324861
PMCPMC6642118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.