ArticleScientific reports2019
Neurotoxicity of organophosphate pesticides could reduce the ability of fish to escape predation under low doses of exposure.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 93 citations in OpenAlex.
- Bioaccumulation of toxic and essential elements and enzymatic responses in native fish from the middle Tocantins River.Scientific reports · 2026Article
- Hepatoprotective role of ascorbic acid against fenvalerate-induced histopathological, ultrastructural, and antioxidant disruptions inToxicology reports · 2025Article
- Single and joint toxicity of ethoprophos and bispyribac-sodium to Oreochromis niloticus: biochemical and genotoxic responses.Fish physiology and biochemistry · 2025Article
- Animal personality in multiple stressor environments: the evolutionary ecology of among-individual differences in responses to stressor suites.Proceedings. Biological sciences · 2024Review
- Domoic acid affects brain morphology and causes behavioral alterations in two fish species.Scientific reports · 2023Article
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- Social behaviors as welfare indicators in teleost fish.Frontiers in veterinary science · 2023Review
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- Pesticide Pollution: Detrimental Outcomes and Possible Mechanisms of Fish Exposure to Common Organophosphates and Triazines.Journal of xenobiotics · 2022Review
- First study on response of astrocytes in alevines of red-bellied pacu (Veterinary world · 2022Article
- Endophytic fungus Phomopsis sp. as a source of 3-nitropropionic acid with larvicidal activity against Aedes aegypti (Linnaeus 1762, Diptera: Culicidae).Revista da Sociedade Brasileira de Medicina Tropical · 2022Article
- Pesticides Burden in Neotropical Rivers: Costa Rica as a Case Study.Molecules (Basel, Switzerland) · 2021Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biomarkers are frequently used in ecotoxicology as they allow to study toxicant effects happening at low concentrations of exposure. However, most sublethal studies only evaluate cellular biomarkers which lack evident ecological relevance. We used a multibiomarker approach to estimate the toxic effects of ethoprophos, an organophosphate insecticide commonly used in banana plantations, on the tropical fish Astyanax aeneus (Characidae). We measured biomarkers at sub-individual (cellular) and individual (metabolism, behavior) levels and examined relationships among these responses. A sublethal exposure to ethoprophos caused a significant (54%) reduction of brain Cholinesterase (ChE) activity, reflecting the pesticide's high neurotoxicity. However, other biomarkers like oxidative stress, biotransformation reactions, and resting metabolic rate were not affected. Exposure to ethoprophos modified antipredator behaviors such as escape response and detection avoidance (light/dark preference): exposed fish escaped slower from a simulated attack and preferred brighter areas in a novel tank. The relationship between ChE activity and reaction time suggests that pesticide-induced ChE inhibition reduces escape ability in fish. Our results provide evidence that impacts of organophosphate pesticides on fish ecological fitness can occur even with short exposures at very low concentrations.
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