Evidence map›Paper›PMID 31324721›Full record

ArticleThe Journal of biological chemistry2019

Metallophosphoesterase regulates light-induced rhodopsin endocytosis by promoting an association between arrestin and the adaptor protein AP2.

Yawen Mu, Yao Tian, Zi Chao Zhang, Junhai Han

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Yawen MuInstitute of Life Sciences, the Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing, 210096, China.
Yao TianInstitute of Life Sciences, the Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing, 210096, China.
Zi Chao ZhangInstitute of Life Sciences, the Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing, 210096, China. Electronic address: zhangzc@seu.edu.cn.
Junhai HanInstitute of Life Sciences, the Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing, 210096, China; Co-innovation Center of Neuroregeneration, Nantong University, Nantong, JS 226001, China. Electronic address: junhaihan@seu.edu.cn.
Southeast University · CNNantong University · CNSoutheast University · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Light-induced endocytosis of rhodopsin in the retina is critical for preventing photoreceptor hyperactivity and for the survival of photoreceptor cells. In

Indexed as

EndocytosisLightAnimalsArrestinDrosophilaPhosphoprotein PhosphatasesRhodopsinTranscription Factor AP-2ArrestinPhosphoprotein PhosphatasesRhodopsinTranscription Factor AP-2arrestinclathrinclathrin adaptor protein AP2endocytosisG protein-coupled receptor (GPCR)metallophosphoesterase (MPPE)photoreceptor functionretinal degenerationrhodopsin

Identifiers

PMID31324721
PMCPMC6721944
OpenAlexW2964324319

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.