Observational studyBMJ open2019
Effect of frailty on quality of life in elderly patients after hip fracture: a longitudinal study.
Observational study in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 42 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevalence, Recovery Patterns and Risk Factors of Non-fatal Outcome and Costs After Trauma; a Prospective Follow up Study
Multicomponent Exercise and Nutrition Based Frailty Intervention in Postoperative Hip Fracture Inpatients
Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Prehabilitation in Frail Patients Undergoing Cancer Surgery: A Systematic Review and Meta-analysis.Annals of surgical oncology · 2025Pooled it
- Prognostic significance of frailty in older patients with hip fracture: a systematic review and meta-analysis.International orthopaedics · 2022Pooled it
- Effects of Frailty on Outcomes Following Surgery Among Patients With Hip Fractures: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2022Pooled it
- Trial
- Position paper: a coordinated approach to fracture and fall prevention from seven international organizations.European geriatric medicine · 2026Article
- Association Between Preoperative Frailty and Postoperative Acute Kidney Injury, Complications, and Resource Utilization in Older Patients Undergoing Hip Fracture Surgery.Geriatrics & gerontology international · 2026Article
- The Association Between Preoperative Mobility and 1-Year Survival Following Hip Fracture Surgery: A Nationwide Population Study.Journal of clinical medicine · 2026Article
- Validity and Reliability of the Thai Version of the Delirium Diagnostic Tool-Provisional (DDT-Pro-TH) in Perioperative Patients With Fragility Hip Fractures.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Investigation of the Medium- and Long-Term Results of a Pioneering Method in the Treatment of Geriatric Intertrochanteric Femur Fractures: Osteosynthesis Using the WALANT Technique.Journal of clinical medicine · 2025Article
- Geriatric Assessment as an Important Tool for Post-Hip Surgery Prognosis in Seniors.Nursing reports (Pavia, Italy) · 2025Article
- The effect of delirium on the association between frailty and postoperative major complications in elderly patients: a mediation analysis.Journal of anesthesia · 2025Article
- Defining optimal orthogeriatric hip fracture care: a delphi consensus approach.European geriatric medicine · 2025Article
- Satisfaction and quality of dying with nonoperative end-of-life care for hospitalized and non-hospitalized frail older patients with (suspected) hip fractures: a combined cohort study.Acta orthopaedica · 2025Article
- Characteristics of older patients undergoing surgery in the UK: SNAP-3, a snapshot observational study.British journal of anaesthesia · 2025Observational
- Patient and proxy perspectives in decision-making for geriatric hip fracture management in the Netherlands: a qualitative study.BMJ open · 2024Article
- Evaluation of Steroid-Induced Osteoporosis Prevention Using Tracing Reports in Collaboration between Hospitals and Community Pharmacists.Pharmacy (Basel, Switzerland) · 2024Article
- Exploring Quality of Life and Mortality in Pertrochanteric Fragility Hip Fractures in Northern Greece: A Single Tertiary Center Study.Journal of clinical medicine · 2024Article
- Article
- Association between anesthesia technique and death after hip fracture repair for patients with COVID-19.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024Article
- Prioritizing patients for hip fracture surgery: the role of frailty and cardiac risk.Frontiers in surgery · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aims of this study were to examine the pattern of changes over time in health status (HS) and quality of life (QoL) in the first year after hip fracture and to quantify the association between frailty at the onset of hip fracture and the change in HS and QoL 1 year later. The major hypothesis was that frailty, a clinical state of increased vulnerability, is a good predictor of QoL in patients recovering from hip fracture.
designProspective, observational, follow-up cohort study.
settingSecondary care. Ten participating centres in Brabant, the Netherlands.
participants1091 patients entered the study and 696 patients completed the study. Patients with a hip fracture aged 65 years and older or proxy respondents for patients with cognitive impairment were included in this study.
main outcome measuresThe primary outcomes were HS (EuroQol-5 Dimensions questionnaire) and capability well-being (ICEpop CAPability measure for Older people). Prefracture frailty was defined with the Groningen Frailty Indicator (GFI), with GFI ≥4 indicating frailty. Participants were followed up at 1 month, 3 months, 6 months and 1 year after hospital admission.
resultsIn total, 371 patients (53.3%) were considered frail. Frailty was negatively associated with HS (β -0.333; 95% CI -0.366 to -0.299), self-rated health (β -21.9; 95% CI -24.2 to -19.6) and capability well-being (β -0.296; 95% CI -0.322 to -0.270) in elderly patients 1 year after hip fracture. After adjusting for confounders, including death, prefracture HS, age, prefracture residential status, prefracture mobility, American Society of Anesthesiologists grading and dementia, associations were weakened but remained significant.
conclusionsWe revealed that frailty is negatively associated with QoL 1 year after hip fracture, even after adjusting for confounders. This finding suggests that early identification of prefracture frailty in patients with a hip fracture is important for prognostic counselling, care planning and the tailoring of treatment. TRIAL REGISTRATION NUMBER: NCT02508675.
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