ArticleeNeuro
Methodological Considerations on the Use of Different Spectral Decomposition Algorithms to Study Hippocampal Rhythms.
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Who cites it
22 citing papers in PubMed.
- Enhanced Taylor-Aris dispersion in slender pulsatile annular channels: Implications for perivascular solute transport.Journal of fluid mechanics · 2026Article
- Spectral dependence as a framework for neural coordination.Current research in neurobiology · 2026Article
- Novelty, Ecological Relevance, and Sexual Receptivity Modulate Neuronal Interactions between the Amygdala and Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Impaired theta and low-gamma directed information flow in the hippocampal-prefrontal circuit underlies working memory deficits in APP/PS1 mice.Behavioral and brain functions : BBF · 2025Article
- Gamma oscillatory complexity conveys behavioral information in hippocampal networks.Nature communications · 2024Article
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- Linking temporal coordination of hippocampal activity to memory function.Frontiers in cellular neuroscience · 2023Review
- Theta dominates cross-frequency coupling in hippocampal-medial entorhinal circuit during awake-behavior in rats.iScience · 2022Article
- Causal dynamics and information flow in parietal-temporal-hippocampal circuits during mental arithmetic revealed by high-temporal resolution human intracranial EEG.Cortex; a journal devoted to the study of the nervous system and behavior · 2022Article
- Electrocorticography to Investigate Age-Related Brain Lateralization on Pediatric Motor Inhibition.Frontiers in neurology · 2022Article
- How Many Gammas? Redefining Hippocampal Theta-Gamma Dynamic During Spatial Learning.Frontiers in behavioral neuroscience · 2022Review
- Golden rhythms as a theoretical framework for cross-frequency organization.Neurons, behavior, data analysis, and theory · 2022Article
- Asymmetric Frequency-Specific Feedforward and Feedback Information Flow between Hippocampus and Prefrontal Cortex during Verbal Memory Encoding and Recall.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
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- Spectrum Degradation of Hippocampal LFP During Euthanasia.Frontiers in systems neuroscience · 2021Article
- Cross-Frequency Power-Power Coupling Analysis: A Useful Cross-Frequency Measure to Classify ICA-Decomposed EEG.Sensors (Basel, Switzerland) · 2020Article
- Floating ideas on theta waves.Behavioral neuroscience · 2020Article
- An investigation into the nonlinear coupling between CA1 layers and the dentate gyrus.Behavioral neuroscience · 2020Article
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7 authors.
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Abstract
Local field potential (LFP) oscillations are primarily shaped by the superposition of postsynaptic currents. Hippocampal LFP oscillations in the 25- to 50-Hz range ("slow γ") are proposed to support memory retrieval independent of other frequencies. However, θ harmonics extend up to 48 Hz, necessitating a study to determine whether these oscillations are fundamentally the same. We compared the spectral analysis methods of wavelet, ensemble empirical-mode decomposition (EEMD), and Fourier transform. EEMD, as previously applied, failed to account for the θ harmonics. Depending on analytical parameters selected, wavelet may convolve over high-order θ harmonics due to the variable time-frequency atoms, creating the appearance of a broad 25- to 50-Hz rhythm. As an illustration of this issue, wavelet and EEMD depicted slow γ in a synthetic dataset that only contained θ and its harmonics. Oscillatory transience cannot explain the difference in approaches as Fourier decomposition identifies ripples triggered to epochs of high-power, 120- to 250-Hz events. When Fourier is applied to high power, 25- to 50-Hz events, only θ harmonics are resolved. This analysis challenges the identification of the slow γ rhythm as a unique fundamental hippocampal oscillation. While there may be instances in which slow γ is present in the rat hippocampus, the analysis presented here shows that unless care is exerted in the application of EEMD and wavelet techniques, the results may be misleading, in this case misrepresenting θ harmonics. Moreover, it is necessary to reconsider the characteristics that define a fundamental hippocampal oscillation as well as theories based on multiple independent γ bands.
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