Evidence map›Paper›PMID 31324367›Full record

ArticleGlobal heart2019

Dissemination and Implementation Program in Hypertension in Rwanda: Report on Initial Training and Evaluation.

Ana A Baumann, Vincent Mutabazi, Angela L Brown, Cole Hooley, Dominic Reeds, Cecile Ingabire, Vedaste Ndahindwa, Aurore Nishimwe, W Todd Cade, Lisa de las Fuentes and 8 more

Abstract read
In one paragraph

Article in Global heart, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ana A BaumannBrown School of Social Work, Washington University in St. Louis, St. Louis, MO, USA.
Vincent MutabaziRegional Alliance for Sustainable Development, Kigali, Rwanda.
Angela L BrownCardiovascular Imaging and Clinical Research Core Laboratory, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, USA.
Cole HooleyBrown School of Social Work, Washington University in St. Louis, St. Louis, MO, USA.
Dominic ReedsDivision of Geriatrics and Nutritional Science, Center for Human Nutrition, Washington University School of Medicine, St. Louis, MO, USA.
Cecile IngabireSchool of Nursing and Midwifery, University of Rwanda, Kigali, Rwanda.
Vedaste NdahindwaSchool of Nursing and Midwifery, University of Rwanda, Kigali, Rwanda.
Aurore NishimweSchool of Health Sciences, University of Rwanda, Kigali, Rwanda.
W Todd CadeProgram in Physical Therapy, Washington University School of Medicine, St. Louis, MO, USA.
Lisa de las FuentesCardiovascular Imaging and Clinical Research Core Laboratory, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, USA; Divisions of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.
Enola K ProctorBrown School of Social Work, Washington University in St. Louis, St. Louis, MO, USA.
Stephen KarengeraRegional Alliance for Sustainable Development, Kigali, Rwanda; EAC RCE-VIHSCM, College of Medicine and Heath Sciences, University of Rwanda, Kigali, Rwanda.
Kenneth B SchecthmanDivisions of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.
Charles W GossDivisions of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.
Kevin YarasheskiC2N Diagnostics, LLC, St. Louis, MO, USA.
Brad NewsomeNational Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Eugene MutimuraRegional Alliance for Sustainable Development, Kigali, Rwanda.
Victor G Davila-RomanCardiovascular Imaging and Clinical Research Core Laboratory, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, USA. Electronic address: vdavila@wustl.edu.

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2M
WOMEN'S HEALTH AGENDAU01AI025903 · NIAID · WASHINGTON UNIVERSITY · PI CLIFFORD, DAVID B · 1987 to 2006
$12.5M
The Implementation of Cognitive Screening and Educational Support to Improve Outcomes of Adolescents and Young Adults with Sickle Cell Disease: From Clinic to the Community and BackU01HL133994 · NHLBI · WASHINGTON UNIVERSITY · PI KING, ALLISON A · 2016 to 2021
$5.2M
Developing T4 Translational Research Capacity for Control of Hypertension in RwandaU24HL136790 · NHLBI · RASD RWANDA · PI MUTIMURA, EUGENE · 2017 to 2020
$596k
NCATS NIH HHS UL1 TR002345NHLBI NIH HHS U01 HL133994NHLBI NIH HHS U24 HL136790NIAID NIH HHS U01 AI025903NIDDK NIH HHS P30 DK056341
6 · The paper itself

Abstract

backgroundCardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide and in low- and middle-income countries, and hypertension (HTN) is a major risk factor for CVD. Although effective evidence-based interventions for control of HTN in high-income countries exist, implementation of these in low- and middle-income countries has been challenging due to limited capacity and infrastructure for late-phase translational research. In Rwanda, the 2015 STEPS NCD (STEPwise Approach to Surveillance of Noncommunicable Diseases) risk survey reported an overall prevalence of HTN of 15% (95% confidence interval [CI]: 13.8 to 16.3) for those ages 15 to 64 years; prevalence increased with increasing age to 39% (95% CI: 35.7 to 43.1) for those ages 55 to 64 years; CVD was the third most common cause of mortality (7%). Suboptimal infrastructure and capacity in Rwanda hinders research and community knowledge for HTN control.

objectivesTo address the issue of suboptimal capacity to implement evidence-based interventions in HTN, this project was designed with the following objectives: 1) to develop a regional needs assessment of infrastructure for dissemination and implementation (D & I) strategies for HTN-CVD control; 2) to develop HTN-CVD research capacity through creation of countrywide resources such as core research facilities and training in the fields of HTN-CVD, D & I, and biostatistics; and 3) to engage and train multiple stakeholders in D & I and HTN-CVD evidence-based interventions.

methodsA weeklong training program in HTN-CVD, biostatistics, and D & I was conducted in Rwanda in August 2018, and pre- and post-D & I training competency questionnaires were administered.

resultsQuestionnaire results show a statistically significant increase in D & I knowledge and skills as a result of training (full scale pre- to post-test scores: 2.12 ± 0.78 vs. 3.94 ± 0.42; p < 0.0001).

conclusionsUsing principles of community engagement and train-the-trainer methods, we will continue to adapt guidelines and treatments for HTN-CVD developed in high-income countries to the context of Rwanda with the goal of establishing a sustainable platform to address the burden of disease from HTN-CVD.

Indexed as

Clinical CompetenceImplementation ScienceBiomedical ResearchCardiologyEducation, Medical, GraduateFemaleHumansHypertensionMalePhysiciansPrevalenceProgram EvaluationRisk FactorsRwanda

Identifiers

PMID31324367
PMCPMC6816501

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.