Evidence map›Paper›PMID 31324268›Full record

ArticleBMC research notes2019

RepViz: a replicate-driven R tool for visualizing genomic regions.

Thomas Faux, Kalle T Rytkönen, Asta Laiho, Laura L Elo

Abstract read
In one paragraph

Article in BMC research notes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas FauxTurku Bioscience Centre, University of Turku and Åbo Akademi University, Tykistökatu 6, 20520, Turku, Finland. thmafa@utu.fi.ORCID http://orcid.org/0000-0002-3878-3368
Kalle T RytkönenTurku Bioscience Centre, University of Turku and Åbo Akademi University, Tykistökatu 6, 20520, Turku, Finland.
Asta LaihoTurku Bioscience Centre, University of Turku and Åbo Akademi University, Tykistökatu 6, 20520, Turku, Finland.
Laura L EloTurku Bioscience Centre, University of Turku and Åbo Akademi University, Tykistökatu 6, 20520, Turku, Finland. laliel@utu.fi.

Funding

Academy of Finland 296801Academy of Finland 304995Academy of Finland 310561Academy of Finland 313343H2020 European Research Council 677943H2020 Marie Skłodowska-Curie Actions 675395Juvenile Diabetes Research Foundation United States of America 2-2013-32Tekes 1877/31/2016
6 · The paper itself

Abstract

objectiveVisualization of sequencing data is an integral part of genomic data analysis. Although there are several tools to visualize sequencing data on genomic regions, they do not offer user-friendly ways to view simultaneously different groups of replicates. To address this need, we developed a tool that allows efficient viewing of both intra- and intergroup variation of sequencing counts on a genomic region, as well as their comparison to the output of user selected analysis methods, such as peak calling.

resultsWe present an R package RepViz for replicate-driven visualization of genomic regions. With ChIP-seq and ATAC-seq data we demonstrate its potential to aid visual inspection involved in the evaluation of normalization, outlier behavior, detected features from differential peak calling analysis, and combined analysis of multiple data types. RepViz is readily available on Bioconductor ( https://www.bioconductor.org/packages/devel/bioc/html/RepViz.html ) and on Github ( https://github.com/elolab/RepViz ).

Indexed as

SoftwareAnimalsComputational BiologyGene Expression ProfilingGenomicsInternetMiceSequence Analysis, DNAComputational genomicsEpigeneticsGenome analysisVisualisation

Identifiers

PMID31324268
PMCPMC6642542

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.