Evidence map›Paper›PMID 31324242›Full record

ArticleBMC oral health2019

Prevalence and factors associated with dental caries in patients attending an HIV care clinic in Uganda: a cross sectional study.

Dunstan Kalanzi, Harriet Mayanja-Kizza, Damalie Nakanjako, Catherine Lutalo Mwesigwa, Ronald Ssenyonga, Bennett T Amaechi

Open access · goldAbstract read
In one paragraph

Article in BMC oral health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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  15. Oral Manifestations Associated with HIV/AIDS Patients.Medicina (Kaunas, Lithuania) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Dunstan KalanziDepartment of Dentistry School of Health Sciences, Makerere University College of Health Sciences, P.O.Box 7072, Kampala, Uganda. dkalanzi@chs.mak.ac.ug.ORCID 0000-0003-0076-8573
Harriet Mayanja-KizzaDepartment of Medicine School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Damalie NakanjakoDepartment of Medicine School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Catherine Lutalo MwesigwaDepartment of Dentistry School of Health Sciences, Makerere University College of Health Sciences, P.O.Box 7072, Kampala, Uganda.
Ronald SsenyongaDepartment of Epidemiology and Biostatistics School of Public Health, Makerere University College of Health Sciences, Kampala, Uganda.
Bennett T AmaechiDepartment of Comprehensive Dentistry, University of Texas Health San Antonio School of Dentistry, San Antonio, TX, USA.
Makerere University · UGThe University of Texas Health Science Center at San Antonio · US

Funding

NURTURE:Research Training and Mentoring Program for Career Development of Faculty at Makerere University College of Health SciencesD43TW010132 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI SEWANKAMBO, NELSON K · 2015 to 2019
$4.3M
FIC NIH HHS D43 TW010132
6 · The paper itself

Abstract

backgroundChronic Human Immunodeficiency Virus (HIV) infection is associated with reduced saliva flow rate due to infiltration of HIV and proliferation of CD8 lymphocytes in salivary glands. It is unclear whether HIV infection and antiretroviral therapy (ART) increase caries risk. This study aimed to determine the prevalence and factors associated with dental caries in HIV infected adults attending the Mulago Immune Suppression Syndrome (ISS) clinic in Uganda.

methodsA cross-sectional study was conducted among HIV infected persons. Dental examinations were performed by two calibrated dentists using the WHO Radke's caries classification criteria and reported using the decayed (D), missing (M), filled (F), teeth (DMFT) index. The prevalence and factors associated with dental caries was examined through linear regression analyses.

resultsOverall, 748 participants (females = 491, 65.6%) with a mean age of 39 ± 9.4 years were included in the final analysis; of whom 83.7% had caries (DMFT> 0), with a significantly (p < 0.05) higher prevalence among females 86.6% than males 78.2%. The mean DMFT was 5.9 ± 5.5, with statistically significant differences based on gender (males 4.9 ± 4.8 and females 6.3 ± 5.9, p < 0.05) and duration on ART (< 2 years 4.8 ± 4.4, > 2 years but < 5 years 5.7 ± 5.5, > 5 years 6.6 ± 6.0 p < 0.05). The majority (67.2%) of participants reported brushing their teeth twice or more a day, and sugar intake was not associated with dental caries.

conclusionCaries prevalence is high among HIV infected adults under care. Duration of ART was associated with increased risk and severity of caries. Therefore, we recommend integration of dental care in HIV treatment programs.

Indexed as

AdultCross-Sectional StudiesDental CariesDMF IndexFemaleHIVHIV InfectionsHumansMaleMiddle AgedPrevalenceUgandaAntiretroviral therapyDental cariesHuman immunodeficiency virus

Identifiers

PMID31324242
PMCPMC6642521
OpenAlexW2963039091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.