Evidence map›Paper›PMID 31324226›Full record

ArticleBMC infectious diseases2019

Seroprevalence and molecular characteristics of varicella-zoster virus infection in Chinese children.

Lin Luan, Xiaochen Shen, Jing Qiu, Yang Jing, Jingqi Zhang, Jie Wang, Jun Zhang, Chen Dong

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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  12. Spatiotemporal Epidemiology of Varicella in Chongqing, China, 2014-2018.International journal of environmental research and public health · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lin LuanSuzhou Center for Disease Control and Prevention, 72 Sanxiang Road, Suzhou, 215000, China.
Xiaochen ShenGusu Center for Disease Control and Prevention, Suzhou, China.
Jing QiuDepartment of Epidemiology and Statistics, School of Public Health, Jiangsu Key Laboratory and Translational Medicine for Geriatric Disease, Medical College of Soochow University, 199 Renai Road, Suzhou, 215123, Jiangsu, China.
Yang JingDepartment of Epidemiology and Statistics, School of Public Health, Jiangsu Key Laboratory and Translational Medicine for Geriatric Disease, Medical College of Soochow University, 199 Renai Road, Suzhou, 215123, Jiangsu, China.
Jingqi ZhangDepartment of Epidemiology and Statistics, School of Public Health, Jiangsu Key Laboratory and Translational Medicine for Geriatric Disease, Medical College of Soochow University, 199 Renai Road, Suzhou, 215123, Jiangsu, China.
Jie WangDepartment of Epidemiology and Statistics, School of Public Health, Jiangsu Key Laboratory and Translational Medicine for Geriatric Disease, Medical College of Soochow University, 199 Renai Road, Suzhou, 215123, Jiangsu, China.
Jun ZhangSuzhou Center for Disease Control and Prevention, 72 Sanxiang Road, Suzhou, 215000, China. sz_zhangj@163.com.
Chen DongDepartment of Epidemiology and Statistics, School of Public Health, Jiangsu Key Laboratory and Translational Medicine for Geriatric Disease, Medical College of Soochow University, 199 Renai Road, Suzhou, 215123, Jiangsu, China. cdong@suda.edu.cn.
Soochow University · CNChinese Center For Disease Control and Prevention · CN

Funding

Young Medical Talents Program of Jiangsu Province of China QNRC2016230
6 · The paper itself

Abstract

backgroundVaricella-zoster virus (VZV) infection in children is an important public health problem in China. We performed the current study to explore the seroprevalence of VZV infection in Chinese children in order to provide more information for improvement of varicella vaccination in China.

methodsThree thousand fourteen children were recruited from Chinese kindergarten students aged from four to six years. Anti-VZV IgG and IgM were assayed using enzyme-linked immunosorbent assay. Both ORF22 and ORF62 of VZV were amplified, sequenced, and analyzed by nested PCR.

resultsAmong 3014 children, 43.9% of boys and 46.3% of girls were vaccinated with varicella vaccine, respectively. The seroprevalence of anti-VZV IgG was 54.4% in the children with varicella vaccination, which was significantly higher than those in unvaccinated children (49.2%) (χ

conclusionsOur study indicated that about half of Chinese children aged four to six years have a high risk of VZV infection. It should be helpful for the evaluation on the necessity of varicella immunization in China.

Indexed as

Antibodies, Anti-IdiotypicChickenpox VaccineChildChild, PreschoolChinaFemaleHerpesvirus 3, HumanHumansMalePhylogenySeroepidemiologic StudiesVaccinationVaricella Zoster Virus InfectionAntibodies, Anti-Idiotypicanti-IgGanti-IgMChickenpox VaccineGenotypeSeroprevalence, vaccinationVaricella-zoster virus

Identifiers

PMID31324226
PMCPMC6642589
OpenAlexW2963369792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.