Evidence map›Paper›PMID 31324196›Full record

ArticleJournal of orthopaedic surgery and research2019

Cement injection and postoperative vertebral fractures during vertebroplasty.

Le Hu, Hao Sun, Hua Wang, Jun Cai, Yuping Tao, Xinmin Feng, Yongxiang Wang

Abstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  7. The impact of different bone cement distribution patterns on cement leakage in percutaneous curved vertebroplasty versus bilateral percutaneous vertebroplasty.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Le HuDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Yangzhou, 225001, China.
Hao SunDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Yangzhou, 225001, China.
Hua WangDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Yangzhou, 225001, China.
Jun CaiDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Yangzhou, 225001, China.
Yuping TaoDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Yangzhou, 225001, China.
Xinmin FengDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Yangzhou, 225001, China.
Yongxiang WangDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Yangzhou, 225001, China. wyx918spine@163.com.ORCID http://orcid.org/0000-0002-2003-6006

Funding

Project of Jiangsu Health Commission H2018022Six Talent Peaks Project in Jiangsu Province WSW-133The 333 talents project in jiangsu province BRA2016159Yangzhou City Science and Education Strengthening Key Discipline YWKJ2018-3
6 · The paper itself

Abstract

objectiveVertebroplasty is the most widely used method for treating osteoporotic vertebral compression fractures (OVCF). During this procedure, bone cement is injected into the vertebral body. Fracture and additional fractures can occur adjacent to the treatment site. Thus, we studied factors causing such vertebral fractures after vertebroplasty and calculated the appropriate amount of bone cement to inject.

methodsFrom September 2012 to March 2016, 187 patients with OVCF undergoing vertebroplasty were selected, and 112 patients with complete follow-up information were selected. Of these, 28 had adjacent vertebral fractures (refracture group) during the follow-up period, and 84 patients had no adjacent vertebral fractures (control group). Then, sex, age, body weight, bone mineral density (BMD), and bone cement injection (bone cement injection volume and bone fracture vertebral volume percent) were compared.

resultsAll patients had significant pain relief within 24 h (preoperative and postoperative [24 h later] VAS scores were 7.4 ± 0.8 and 2.3 ± 0.5, respectively). The age and weight were not statistically significantly different (P > 0.05). BMD values were statistically significantly different between groups as was sex (P < 0.05).

conclusionsBone cement injection volume, BMD values, and sex were statistically significantly related to adjacent vertebral fractures after vertebroplasty, and cement injection volumes exceeding 40.5% caused adjacent vertebral fractures.

Indexed as

AgedAged, 80 and overBone CementsFemaleFractures, CompressionHumansLumbar VertebraeMaleOsteoporotic FracturesPostoperative ComplicationsRisk FactorsSex FactorsSpinal FracturesThoracic VertebraeTreatment OutcomeVertebroplastyBone CementsAdjacent vertebral fracturesBone cement injection rateOsteoporotic vertebral compression fractures (OVCF)Percutaneous vertebroplasty

Identifiers

PMID31324196
PMCPMC6642552

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.