Evidence map›Paper›PMID 31324154›Full record

ArticleBMC nephrology2019

Evaluation of the chemical composition of nephrolithiasis using dual-energy CT in Southern Chinese gout patients.

Zhao-Xia Li, Gen-Long Jiao, Shu-Min Zhou, Zhong Yuan Cheng, Shoaib Bashir, Yi Zhou

Abstract read
In one paragraph

Article in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhao-Xia LiDepartment of Rheumatology, The First Affiliated Hospital, Jinan University, No. 613 West Huangpu Ave, Tianhe District, Guangzhou, 510630, China.
Gen-Long JiaoDepartment of Orthopedics, The First Affiliated Hospital, Jinan University, NO.613 West Huangpu Ave,Tianhe District, Guangzhou, 510630, China.
Shu-Min ZhouDepartment of Rheumatology, The First Affiliated Hospital, Jinan University, No. 613 West Huangpu Ave, Tianhe District, Guangzhou, 510630, China.
Zhong Yuan ChengMedical Imaging Center, The First Affiliated Hospital, Jinan University, No.613 West Huangpu Ave,Tianhe District, Guangzhou, 510630, China.
Shoaib BashirDepartment of Rheumatology, The First Affiliated Hospital, Jinan University, No. 613 West Huangpu Ave, Tianhe District, Guangzhou, 510630, China.
Yi ZhouDepartment of Rheumatology, The First Affiliated Hospital, Jinan University, No. 613 West Huangpu Ave, Tianhe District, Guangzhou, 510630, China. zhou21yi@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA study to evaluate the prevalence of uric acid (UA) nephrolithiasis with dual-energy CT (DECT) and explore the risk factors for kidney stones in primary gout patients.

methodsEighty-four consecutive gout patients underwent urinary tract ultrasonography or DECT to confirm the existence of kidney stones. Urine and blood samples were also taken for laboratory analysis.

resultsForty-one subjects (48.8%) had nephrolithiasis diagnosed; 38 had a kidney stone. Thirty-two of the 38 patients underwent a DECT scan, and 27 patients had nephrolithiasis in DECT. Among them, 63.0% (17/27) and 14.8% (4/21) of the patients had pure UA and UA-based mixed stone, respectively, and 22.2% (6/27) had a non-UA stone. Those with nephrolithiasis suffered from more frequent acute attacks and had longer disease durations of gout. At least one urine biochemical abnormality was found in 81% of patients. Forty-four (55.0%) patients presented hypomagnesuria. Forty-three (51.8%) patients had low urine volume. Unduly acidic urine (UAU) was present in 36 patients (44.4%). Hyperuricosuria was only found in ten (12.2%) patients. In comparison to the non-lithiasic group, the lithiasic group was more likely to have a UAU. Binary logistic regression showed that female gender was a protective factor, while disease duration of gout and low urine pH were risk factors for nephrolithiasis.

conclusionOur results indicated that nephrolithiasis, especially UA stones, were more common than previous reports in gout patients indicated, and that disease duration of gout, and low urine pH, were risk factors for nephrolithiasis.

Indexed as

Tomography, X-Ray ComputedAdultAgedChinaFemaleGoutHumansKidney CalculiMaleMiddle AgedNephrolithiasisPrevalenceUric AcidUric AcidBiochemical abnormalityDual-energy computed tomographyNephrolithiasisPrimary goutRisk factor

Identifiers

PMID31324154
PMCPMC6642481

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.