Evidence map›Paper›PMID 31324059›Full record

ArticleInternational journal of molecular sciences2019

Interleukin-10 Facilitates Glutamatergic Synaptic Transmission and Homeostatic Plasticity in Cultured Hippocampal Neurons.

Miroslav N Nenov, Maxim V Konakov, Ilia Y Teplov, Sergey G Levin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

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  5. Deletion of p75Frontiers in molecular neuroscience · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Miroslav N NenovInstitute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences, Pushchino, Moscow 142290, Russia. nenovmir@gmail.com.
Maxim V KonakovInstitute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences, Pushchino, Moscow 142290, Russia.
Ilia Y TeplovInstitute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences, Pushchino, Moscow 142290, Russia.
Sergey G LevinInstitute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences, Pushchino, Moscow 142290, Russia.
Institute of Theoretical and Experimental Biophysics · RU

Funding

Russian Science Foundation 16-15-10356
6 · The paper itself

Abstract

Anti-inflammatory cytokines are known to exert neuroprotective action ameliorating aberrant neuronal network activity associated with inflammatory responses. Yet, it is still not fully understood if anti-inflammatory cytokines play a significant role in the regulation of synaptic activity under normal conditions. Thus, the aim of our study was to investigate the effect of Interleukin-10 (IL-10) on neuronal synaptic transmission and plasticity. For this we tested the effect of IL-10 on miniature excitatory postsynaptic currents (mEPSC) and intracellular Ca

Indexed as

AlanineAnimalsCells, CulturedHippocampusInterleukin-10Microscopy, FluorescenceNeuronal PlasticityNeuronsPatch-Clamp TechniquesPyrimidinesRatsRats, Sprague-DawleySynaptic TransmissionTetrodotoxin5-fluorowillardiineAlanineInterleukin-10PyrimidinesTetrodotoxinexcitatory glutamatergic synaptic transmissionhomeostatic synaptic plasticityInterleukin-10mEPSCprimary hippocampal culture

Identifiers

PMID31324059
PMCPMC6650830
OpenAlexW2959011057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.