Evidence map›Paper›PMID 31324026›Full record

ArticleJournal of clinical medicine2019

Exploration of Artificial Intelligence Use with ARIES in Multiple Myeloma Research.

Sophia Loda, Jonathan Krebs, Sophia Danhof, Martin Schreder, Antonio G Solimando, Susanne Strifler, Leo Rasche, Martin Kortüm, Alexander Kerscher, Stefan Knop and 3 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sophia LodaDepartment of Internal Medicine II, University Hospital Würzburg, 97080 Würzburg, Germany. Loda_S@ukw.de.ORCID 0000-0001-5724-0812
Jonathan KrebsChair for Artificial Intelligence and Applied Informatics, University of Würzburg, 97070 Würzburg, Germany.
Sophia DanhofDepartment of Internal Medicine II, University Hospital Würzburg, 97080 Würzburg, Germany.
Martin SchrederI. Medical Department, Wilheminen Hospital, 1160 Vienna, Austria.
Antonio G SolimandoDepartment of Biomedical Sciences and Human Oncology, Section of Internal Medicine 'G. Baccelli', University of Bari Medical School Bari, 70124 Bari, Italy.ORCID 0000-0002-2293-9698
Susanne StriflerDepartment of Internal Medicine II, University Hospital Würzburg, 97080 Würzburg, Germany.
Leo RascheDepartment of Internal Medicine II, University Hospital Würzburg, 97080 Würzburg, Germany.
Martin KortümDepartment of Internal Medicine II, University Hospital Würzburg, 97080 Würzburg, Germany.
Alexander KerscherComprehensive Cancer Center, 97080 Würzburg, Germany.ORCID 0000-0001-7742-570X
Stefan KnopDepartment of Internal Medicine II, University Hospital Würzburg, 97080 Würzburg, Germany.
Frank PuppeChair for Artificial Intelligence and Applied Informatics, University of Würzburg, 97070 Würzburg, Germany.
Hermann EinseleDepartment of Internal Medicine II, University Hospital Würzburg, 97080 Würzburg, Germany.
Max BittrichDepartment of Internal Medicine II, University Hospital Würzburg, 97080 Würzburg, Germany. Bittrich_M@ukw.de.ORCID 0000-0003-0917-4173

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNatural language processing (NLP) is a powerful tool supporting the generation of Real-World Evidence (RWE). There is no NLP system that enables the extensive querying of parameters specific to multiple myeloma (MM) out of unstructured medical reports. We therefore created a MM-specific ontology to accelerate the information extraction (IE) out of unstructured text.

methodsOur MM ontology consists of extensive MM-specific and hierarchically structured attributes and values. We implemented "A Rule-based Information Extraction System" (ARIES) that uses this ontology. We evaluated ARIES on 200 randomly selected medical reports of patients diagnosed with MM.

resultsOur system achieved a high F1-Score of 0.92 on the evaluation dataset with a precision of 0.87 and recall of 0.98.

conclusionsOur rule-based IE system enables the comprehensive querying of medical reports. The IE accelerates the extraction of data and enables clinicians to faster generate RWE on hematological issues. RWE helps clinicians to make decisions in an evidence-based manner. Our tool easily accelerates the integration of research evidence into everyday clinical practice.

Indexed as

artificial intelligencemultiple myelomanatural language processingontologyreal world evidence

Identifiers

PMID31324026
PMCPMC6678083

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.