Evidence map›Paper›PMID 31324003›Full record

ArticleCells2019

Hepatocellular Toxicity of Paris Saponins I, II, VI and VII on Two Kinds of Hepatocytes-HL-7702 and HepaRG Cells, and the Underlying Mechanisms.

Wenping Wang, Yi Liu, Mingyi Sun, Na Sai, Longtai You, Xiaoxv Dong, Xingbin Yin, Jian Ni

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 33 citations in OpenAlex.

  1. The genusHorticulture research · 2025
    Article
  2. The role ofHeliyon · 2024
    Review
  3. Article
  4. Article
  5. Review
  6. Separation and Purification of Two Saponins fromMolecules (Basel, Switzerland) · 2022
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Wenping WangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China.ORCID 0000-0002-9488-9474
Yi LiuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China.
Mingyi SunSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China.
Na SaiSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China.
Longtai YouSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China.ORCID 0000-0002-5600-353X
Xiaoxv DongSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China. dxiaoxv@163.com.
Xingbin YinSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China. yxbtcm@163.com.
Jian NiBeijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100102, China. njtcm@263.net.
Beijing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApoptosisCaspasesCell Cycle CheckpointsCell LineCytochromes cHepatocytesHumansL-Lactate DehydrogenasePoly(ADP-ribose) PolymerasesReactive Oxygen SpeciesSaponinsTumor Suppressor Protein p53CaspasesCytochromes cL-Lactate DehydrogenasePoly(ADP-ribose) PolymerasesReactive Oxygen SpeciesSaponinsTumor Suppressor Protein p53activation of death receptorBcl-2 proteinscell apoptosisParis saponins I, II, VI, and VIIROS generation

Identifiers

PMID31324003
PMCPMC6678998
OpenAlexW2962069749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.