Evidence map›Paper›PMID 31323993›Full record

ArticleMolecules (Basel, Switzerland)2019

Similar Safety Profile of the Enantiomeric N-Aminoalkyl Derivatives of

Karolina Słoczyńska, Paulina Koczurkiewicz, Kamil Piska, Beata Powroźnik, Katarzyna Wójcik-Pszczoła, Katarzyna Klaś, Magdalena Wyszkowska-Kolatko, Elżbieta Pękala

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Karolina SłoczyńskaDepartment of Pharmaceutical Biochemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland.ORCID 0000-0002-7366-2676
Paulina KoczurkiewiczDepartment of Pharmaceutical Biochemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland. paulina.koczurkiewicz@uj.edu.pl.
Kamil PiskaDepartment of Pharmaceutical Biochemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland.
Beata PowroźnikDepartment of Pharmaceutical Biochemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland.
Katarzyna Wójcik-PszczołaDepartment of Pharmaceutical Biochemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland.
Katarzyna KlaśDepartment of Pharmaceutical Biochemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland.
Magdalena Wyszkowska-KolatkoDepartment of Pharmaceutical Biochemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland.
Elżbieta PękalaDepartment of Pharmaceutical Biochemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland.ORCID 0000-0002-1260-4253
Jagiellonian University · PL

Funding

Uniwersytet Jagielloński Collegium Medicum K/DSC/005332Uniwersytet Jagielloński Collegium Medicum K/ZDS/007826
6 · The paper itself

Abstract

Epilepsy is one of the most common neurological disorder in the world. Many antiepileptic drugs cause multiple adverse effects. Moreover, multidrug resistance is a serious problem in epilepsy treatment. In the present study we evaluated the safety profile of three (

Indexed as

Activation, MetabolicAnticonvulsantsAntimutagenic AgentsATP Binding Cassette Transporter, Subfamily B, Member 1BiotransformationCyclohexanolsDose-Response Relationship, DrugHumansLiverMolecular StructureMutagens2-aminocyclohexanolAnticonvulsantsAntimutagenic AgentsATP Binding Cassette Transporter, Subfamily B, Member 1CyclohexanolsMutagensaminocyclohexanolcytotoxicityenantiomersepilepsymutagenicityP-glycoprotein

Identifiers

PMID31323993
PMCPMC6651381
OpenAlexW2958304943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.