Evidence map›Paper›PMID 31323958›Full record

ArticleCancers2019

Furanoic Lipid F-6, A Novel Anti-Cancer Compound that Kills Cancer Cells by Suppressing Proliferation and Inducing Apoptosis.

Jassim M Al-Hassan, Yuan Fang Liu, Meraj A Khan, Peiying Yang, Rui Guan, Xiao-Yan Wen, Mohammad Afzal, Sosamma Oommen, Bincy M Paul, Divya Nair and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Jassim M Al-HassanDepartment of Biological Sciences, Faculty of Science, Kuwait University, Safat 13060, Kuwait.
Yuan Fang LiuProgram in Translational Medicine, Peter Gilgan Centre for Research and Learning (PGCRL), The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Meraj A KhanProgram in Translational Medicine, Peter Gilgan Centre for Research and Learning (PGCRL), The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Peiying YangDepartment of Palliative, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Rui GuanZebrafish Centre for Advanced Drug Discovery & Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON M5B 1W8, Canada.
Xiao-Yan WenZebrafish Centre for Advanced Drug Discovery & Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON M5B 1W8, Canada.
Mohammad AfzalDepartment of Biological Sciences, Faculty of Science, Kuwait University, Safat 13060, Kuwait.
Sosamma OommenDepartment of Zoology, CMS College, Kottayam 686001, India.ORCID 0000-0002-3365-2553
Bincy M PaulDepartment of Biological Sciences, Faculty of Science, Kuwait University, Safat 13060, Kuwait.
Divya NairDepartment of Biological Sciences, Faculty of Science, Kuwait University, Safat 13060, Kuwait.
Nades PalaniyarProgram in Translational Medicine, Peter Gilgan Centre for Research and Learning (PGCRL), The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.ORCID 0000-0002-2170-8548
Cecil Pace-AsciakProgram in Translational Medicine, Peter Gilgan Centre for Research and Learning (PGCRL), The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada. cecil.pace-asciak@sickkids.ca.
Kuwait University · KWHospital for Sick Children · CASt. Michael's Hospital · CAUniversity of Toronto · CAGovernment Medical College · INThe University of Texas MD Anderson Cancer Center · US

Funding

Cystic Fibrosis Canada 3180Kuwait Foundation for the Advancement of Sciences 2013-120701 A-C
6 · The paper itself

Abstract

Identifying novel anti-cancer drugs is important for devising better cancer treatment options. In a series of studies designed to identify novel therapeutic compounds, we recently showed that a C-20 fatty acid (12,15-epoxy-13,14-dimethyleicosa-12,14-dienoic acid, a furanoic acid or F-6) present in the lipid fraction of the secretions of the Arabian Gulf catfish skin (

Indexed as

apoptosiscancer cell linescell proliferationcell recoveryF-6 (furanoic F-acid)Gulf catfish lipids

Identifiers

PMID31323958
PMCPMC6678287
OpenAlexW2961930566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.