Evidence map›Paper›PMID 31323940›Full record

ArticleJournal of clinical medicine2019

Assessing Developmental Environmental Risk Factor Exposure in Clinical High Risk for Psychosis Individuals: Preliminary Results Using the Individual and Structural Exposure to Stress in Psychosis-Risk States Scale.

Teresa Vargas, Denise S Zou, Rachel E Conley, Vijay A Mittal

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Teresa VargasDepartment of Psychology, Northwestern University, Evanston, IL 60208, USA. teresavargas@u.northwestern.edu.ORCID 0000-0001-9104-9130
Denise S ZouDepartment of Psychology, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0003-4694-1247
Rachel E ConleyDepartment of Psychology, Northwestern University, Evanston, IL 60208, USA.
Vijay A MittalDepartment of Psychology, Department of Psychiatry, Department of Medical Social Sciences, Institute for Innovations in Developmental Sciences, Institute for Policy Research, Northwestern University, Evanston, IL 60208, USA.
Northwestern University · US

Funding

2/3 Community psychosis risk screening: An instrument development studyR01MH112545 · NIMH · NORTHWESTERN UNIVERSITY · PI MITTAL, VIJAY A · 2017 to 2021
$1.2M
Exercise and markers of medial temporal health in youth at-risk for psychosisR21MH103231 · NIMH · UNIVERSITY OF COLORADO · PI BRYAN, ANGELA, MITTAL, VIJAY A · 2014 to 2015
$489k
Neural Habituation in Ultra High-Risk YouthR21MH110374 · NIMH · NORTHWESTERN UNIVERSITY · PI MITTAL, VIJAY A · 2017 to 2018
$445k
National Institute of Mental Health R01MH112545National Institute of Mental Health R21MH110374National Institute of Mental Health R21/R33MH103231
6 · The paper itself

Abstract

introductionExposure to cumulative environmental risk factors across development has been linked to a host of adverse health/functional outcomes. This perspective incorporating information regarding exposure at differing developmental periods is lacking in research surrounding individuals at Clinical High Risk (CHR) for developing a psychotic disorder.

methodsCHR individuals (

resultsSignificant group differences were not observed for lifetime cumulative events, though CHR trended toward endorsing more events and greater stress severity. For stress severity across development, there were trending group differences for the 11-13 age range, and significant group differences for the 14-18 age range; notably, comparisons for earlier time points did not approach statistical significance. Associations between negative symptoms and cumulative severity of exposure were observed. DISCUSSION: Results suggest exploring exposure to cumulative environmental risk factors/stressors and stress severity across developmental periods is generally informative and possibly specifically so for predictive models and diathesis-stress psychosis risk conceptualizations.

Indexed as

chronic stressclinical high riskcumulative environmental risk factorsdevelopmentdevelopmental stressenvironmental risk factorsenvironmental stresspsychosis

Identifiers

PMID31323940
PMCPMC6678455
OpenAlexW2961783472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.