Evidence map›Paper›PMID 31323932›Full record

ArticleMolecules (Basel, Switzerland)2019

Anti-Multiple Myeloma Potential of Secondary Metabolites from

Alessio Malacrida, Valeria Cavalloro, Emanuela Martino, Arianna Cassetti, Gabriella Nicolini, Roberta Rigolio, Guido Cavaletti, Barbara Mannucci, Francesca Vasile, Marcello Di Giacomo and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Syntheses, structures and anti-cancer activities of CuActa crystallographica. Section E, Crystallographic communications · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Alessio MalacridaSchool of Medicine and Surgery, University of Milan-Bicocca, 20900 Monza, Italy.
Valeria CavalloroDepartment of Earth and Environmental Sciences, University of Pavia, 27100 Pavia, Italy.
Emanuela MartinoDepartment of Earth and Environmental Sciences, University of Pavia, 27100 Pavia, Italy. emanuela.martino@unipv.it.ORCID 0000-0001-9591-4996
Arianna CassettiCREA, Research Centre for Vegetable and Ornamental Crops, 18038 Sanremo, Italy.
Gabriella NicoliniSchool of Medicine and Surgery, University of Milan-Bicocca, 20900 Monza, Italy.ORCID 0000-0002-6241-4538
Roberta RigolioSchool of Medicine and Surgery, University of Milan-Bicocca, 20900 Monza, Italy.
Guido CavalettiSchool of Medicine and Surgery, University of Milan-Bicocca, 20900 Monza, Italy.ORCID 0000-0003-4128-2406
Barbara MannucciCenter of Large Equipment, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-7371-7243
Francesca VasileDepartment of Chemistry, University of Milan, 20133 Milano, Italy.ORCID 0000-0002-3926-8261
Marcello Di GiacomoDepartment of Drug Sciences, University of Pavia, 27100 Pavia, Italy.
Simona CollinaDepartment of Drug Sciences, University of Pavia, 27100 Pavia, Italy. simona.collina@unipv.it.ORCID 0000-0002-2954-7558
Mariarosaria MilosoSchool of Medicine and Surgery, University of Milan-Bicocca, 20900 Monza, Italy. mariarosaria.miloso@unimib.it.
University of Milano-Bicocca · ITUniversity of Pavia · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) belongs to hematological cancers and its incidence is increasing worldwide. Despite recent advances in its therapy, MM still causes many deaths every year. In fact, current therapies sometimes fail and are associated with severe adverse effects, including neurotoxicity. As a part of our ongoing efforts to discover new potential therapies against MM, we prepared

Indexed as

Antineoplastic Agents, PhytogenicCell Line, TumorChemical FractionationChromatography, High Pressure LiquidHibiscusHumansMass SpectrometryMolecular StructureMultiple MyelomaPlant ExtractsSecondary MetabolismSpectrometry, Mass, Electrospray IonizationAntineoplastic Agents, PhytogenicPlant Extractsbioguided assay fractionationHib-carbaldehydeHib-esterHibiscus sabdariffaMultiple myelomanature-aided drug discovery

Identifiers

PMID31323932
PMCPMC6651714
OpenAlexW2959201832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.